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- W2913234047 abstract "Abstract A new indoleglycerol, designated as arecine ( 1 ), and twenty‐three known diketopiperazines 2 – 24 were isolated from the endophytic fungus Diaporthe arecae associated with mangrove Kandelia obovate . Structures of all secondary metabolites 1 – 24 were identified on the basis of their spectrometric data, especially the nuclear magnetic resonance, optical rotation, and mass data. The absolute stereochemistry of compound 1 was determined by comparing its experimental electronic circular dichroism spectrum to those of in silico generated. Moreover, the 1 H and 13 C NMR spectroscopic data of isolated diketopiperazines 3 – 24 were measured in dimethyl sulfoxide‐ d 6 and presented in Table 2 for a convenient comparison. Pharmacological study showed cordysinin A ( 2 ) possessed mild anti‐angiogenic activity, which suppressed tube formation with an IC 50 value of 15.1±0.2 μg/mL." @default.
- W2913234047 created "2019-02-21" @default.
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- W2913234047 date "2019-02-13" @default.
- W2913234047 modified "2023-10-18" @default.
- W2913234047 title "Natural Products from <i>Diaporthe arecae</i> with Anti‐Angiogenic Activity" @default.
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- W2913234047 doi "https://doi.org/10.1002/ijch.201800158" @default.
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