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• W2913238843 abstract "In this work, a biocompatible and stretchable double-carrier drug delivery system was developed for wound dressing application. Quinolone antibiotics enoxacin (ENO) was loaded into Mg-Al layered double hydroxide (LDH) first, and then the as-prepared LDH-ENO nanoparticles were incorporated into polyurethane-polyvinyl alcohol (PU-PVA) hydrogel to build a double-carrier drug delivery system. The results suggested that the introduction of the LDH-ENO nanoparticles into PU-PVA network significantly improved the mechanical properties and biocompatibility of PU-PVA hydrogel. The PU-PVA/LDH-ENO nanocomposite hydrogel, as a double-carrier, obviously delayed the release of the ENO molecules. It suggests that PU-PVA/LDH-ENO nanocomposite hydrogel should be a promising candidate for wound healing applications, especially for the healing of chronic wounds." @default.
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• W2913238843 date "2019-05-01" @default.
• W2913238843 modified "2023-10-17" @default.
• W2913238843 title "Double-carrier drug delivery system based on polyurethane-polyvinyl alcohol/layered double hydroxide nanocomposite hydrogel" @default.
• W2913238843 cites W1741602571 @default.
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• W2913238843 doi "https://doi.org/10.1016/j.matlet.2019.01.151" @default.
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