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- W2913267311 abstract "We read with interest the letter to the editor referring to our work. We acknowledge the fact that we proposed only a point-of-principle study, which was not able to convince the potential readership. We believe anyway that any “big story” starts with small steps and we consider our work as a preliminary step toward a solution. Re: Phé et al.: Involvement of Connexins 43 and 45 in Functional Mechanism of Human Detrusor Overactivity in Neurogenic Bladder (Urology 2013;81:1108.e1-e6)UrologyVol. 82Issue 4PreviewWe read with interest the work by Phé et al1 that reported that connexin (Cx) 43 and Cx 45 selective inhibition reduced the in vitro bladder contractile activity induced by carbachol in the bladder strips from patients with neurogenic detrusor overactivity, but it had no effect on the strips from the control patients. However, Cx 43 selective inhibition did not significantly inhibit the tonic contractions of strips with detrusor only. The authors concluded that Cx 43 exerts its functional role in the mucosa, which agreed with its predominant expression in the mucosa of the rat bladder, as previously reported by Ikeda et al. Full-Text PDF" @default.
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- W2913267311 date "2013-10-01" @default.
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- W2913267311 title "Reply by the Authors" @default.
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- W2913267311 doi "https://doi.org/10.1016/j.urology.2013.06.002" @default.
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