FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913337636> ?p ?o ?g. }

• W2913337636 abstract "Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with several potentially lethal complications. Higher levels of CD3+ T cells in the graft have been associated with increased risk of graft-versus-host-disease (GVHD), but also beneficial graft-versus-leukemia and reduced infections. To tackle post-transplant complications, donor lymphocyte infusions have been used but with increased risk of GVHD. To reduce this risk, we performed depletion of αβ T-cells and treated 12 patients post-HSCT suffering from infections and/or poor immune reconstitution. The αβ T-cell depleted cell products were characterized by flow cytometry. The median log depletion of αβ T-cells was -4.3 and the median yield of γδ T-cells was 73.5%. The median CD34+ cell dose was 4.4×106/kg. All 12 patients were alive 3 months after infusion and after 1 year, two patients had died. No infusion-related side effects were reported and no severe acute GVHD (grade III-IV) developed in any patient post-infusion. Overall, 3 months after infusion 11 out of 12 patients had increased levels of platelets and/or granulocytes. In conclusion, we describe the use of αβ T cell depleted products as stem cell boosters with encouraging results." @default.
• W2913337636 created "2019-02-21" @default.
• W2913337636 creator A5005573514 @default.
• W2913337636 creator A5018698317 @default.
• W2913337636 creator A5024043043 @default.
• W2913337636 creator A5029318700 @default.
• W2913337636 creator A5037254295 @default.
• W2913337636 creator A5042539600 @default.
• W2913337636 creator A5071093438 @default.
• W2913337636 creator A5079082437 @default.
• W2913337636 creator A5080055664 @default.
• W2913337636 date "2019-02-11" @default.
• W2913337636 modified "2023-10-18" @default.
• W2913337636 title "Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion" @default.
• W2913337636 cites W1512693074 @default.
• W2913337636 cites W1603504083 @default.
• W2913337636 cites W1971290387 @default.
• W2913337636 cites W1999057995 @default.
• W2913337636 cites W2010209903 @default.
• W2913337636 cites W2021445530 @default.
• W2913337636 cites W2022625735 @default.
• W2913337636 cites W2027951667 @default.
• W2913337636 cites W2033477620 @default.
• W2913337636 cites W2054671000 @default.
• W2913337636 cites W2064873408 @default.
• W2913337636 cites W2070300530 @default.
• W2913337636 cites W2074856848 @default.
• W2913337636 cites W2086024031 @default.
• W2913337636 cites W2116523595 @default.
• W2913337636 cites W2118802947 @default.
• W2913337636 cites W2118861593 @default.
• W2913337636 cites W2121867806 @default.
• W2913337636 cites W2133694799 @default.
• W2913337636 cites W2135410703 @default.
• W2913337636 cites W2155918243 @default.
• W2913337636 cites W2160624077 @default.
• W2913337636 cites W2325413481 @default.
• W2913337636 cites W2345422165 @default.
• W2913337636 cites W2403928174 @default.
• W2913337636 cites W2523537011 @default.
• W2913337636 cites W2524483961 @default.
• W2913337636 cites W2590092547 @default.
• W2913337636 cites W2621546725 @default.
• W2913337636 cites W2791536803 @default.
• W2913337636 doi "https://doi.org/10.3389/fimmu.2019.00189" @default.
• W2913337636 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6378311" @default.
• W2913337636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30804948" @default.
• W2913337636 hasPublicationYear "2019" @default.
• W2913337636 type Work @default.
• W2913337636 sameAs 2913337636 @default.
• W2913337636 citedByCount "9" @default.
• W2913337636 countsByYear W29133376362019 @default.
• W2913337636 countsByYear W29133376362020 @default.
• W2913337636 countsByYear W29133376362021 @default.
• W2913337636 countsByYear W29133376362022 @default.
• W2913337636 countsByYear W29133376362023 @default.
• W2913337636 crossrefType "journal-article" @default.
• W2913337636 hasAuthorship W2913337636A5005573514 @default.
• W2913337636 hasAuthorship W2913337636A5018698317 @default.
• W2913337636 hasAuthorship W2913337636A5024043043 @default.
• W2913337636 hasAuthorship W2913337636A5029318700 @default.
• W2913337636 hasAuthorship W2913337636A5037254295 @default.
• W2913337636 hasAuthorship W2913337636A5042539600 @default.
• W2913337636 hasAuthorship W2913337636A5071093438 @default.
• W2913337636 hasAuthorship W2913337636A5079082437 @default.
• W2913337636 hasAuthorship W2913337636A5080055664 @default.
• W2913337636 hasBestOaLocation W29133376361 @default.
• W2913337636 hasConcept C10205521 @default.
• W2913337636 hasConcept C109159458 @default.
• W2913337636 hasConcept C126322002 @default.
• W2913337636 hasConcept C1491633281 @default.
• W2913337636 hasConcept C203014093 @default.
• W2913337636 hasConcept C2776090121 @default.
• W2913337636 hasConcept C2777408962 @default.
• W2913337636 hasConcept C2778461978 @default.
• W2913337636 hasConcept C2779695342 @default.
• W2913337636 hasConcept C2779972918 @default.
• W2913337636 hasConcept C28328180 @default.
• W2913337636 hasConcept C2911091166 @default.
• W2913337636 hasConcept C54355233 @default.
• W2913337636 hasConcept C553184892 @default.
• W2913337636 hasConcept C71924100 @default.
• W2913337636 hasConcept C86803240 @default.
• W2913337636 hasConcept C8891405 @default.
• W2913337636 hasConcept C90924648 @default.
• W2913337636 hasConceptScore W2913337636C10205521 @default.
• W2913337636 hasConceptScore W2913337636C109159458 @default.
• W2913337636 hasConceptScore W2913337636C126322002 @default.
• W2913337636 hasConceptScore W2913337636C1491633281 @default.
• W2913337636 hasConceptScore W2913337636C203014093 @default.
• W2913337636 hasConceptScore W2913337636C2776090121 @default.
• W2913337636 hasConceptScore W2913337636C2777408962 @default.
• W2913337636 hasConceptScore W2913337636C2778461978 @default.
• W2913337636 hasConceptScore W2913337636C2779695342 @default.
• W2913337636 hasConceptScore W2913337636C2779972918 @default.
• W2913337636 hasConceptScore W2913337636C28328180 @default.
• W2913337636 hasConceptScore W2913337636C2911091166 @default.
• W2913337636 hasConceptScore W2913337636C54355233 @default.
• W2913337636 hasConceptScore W2913337636C553184892 @default.
• W2913337636 hasConceptScore W2913337636C71924100 @default.

• next