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- W2913362994 startingPage "264" @default.
- W2913362994 abstract "Depression is the most common perinatal psychiatric disorder, but little is known about how it may impact offspring neurodevelopment, as well as the mechanisms by which it may confer transgenerational psychiatric risk. This review presents imaging studies conducted to evaluate the relationship between perinatal depression (PND) and infant and child neurodevelopment. Altered structural and functional connectivity is implicated in children exposed to PND and anxiety. Overall, there are changes in connectivity between amygdala and the prefrontal cortex. Studies suggest decreased hippocampal growth in the first 6 months after birth, decreased cortical thickness in children, and increased amygdala volumes, that are more pronounced in female offspring. Future research is needed to understand the impact of PND on development so that early interventions which promote mother-infant bonding and cognitive development may improve developmental outcomes in children exposed to PND, reducing later risk of psychopathology." @default.
- W2913362994 created "2019-02-21" @default.
- W2913362994 creator A5010833072 @default.
- W2913362994 creator A5019708080 @default.
- W2913362994 creator A5048538795 @default.
- W2913362994 creator A5081287037 @default.
- W2913362994 date "2019-01-31" @default.
- W2913362994 modified "2023-10-14" @default.
- W2913362994 title "Examining the relationship between perinatal depression and neurodevelopment in infants and children through structural and functional neuroimaging research" @default.
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