Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913372231> ?p ?o ?g. }
- W2913372231 endingPage "39" @default.
- W2913372231 startingPage "15" @default.
- W2913372231 abstract "Plant microRNAs are an endogenous class of small regulatory RNA central to the posttranscriptional regulation of gene expression in plant development and environmental stress adaptation or in response to pathogen challenge. The plant microRNA pathway is readily separated into two distinct stages: (1) the production stage, which is localized to the plant cell nucleus and where the microRNA small RNA is processed from a double-stranded RNA precursor transcript, and (2) the action stage, which is localized to the plant cell cytoplasm and where the mature microRNA small RNA is loaded into an effector complex and is used by the complex as a sequence specificity guide to direct expression repression of target genes harboring highly complementary microRNA target sequences. Historical research indicated that the plant microRNA pathway was a highly structured, almost linear pathway requiring a small set of core machinery proteins. However, contemporary research has demonstrated that the plant microRNA pathway is highly dynamic, and to allow for this flexibility, a large and highly functionally diverse set of machinery proteins is now known to be required. For example, recent research has shown that plant microRNAs can regulate target gene expression via a translational repression mechanism of RNA silencing in addition to the standard messenger RNA cleavage-based mechanism of RNA silencing: a mode of RNA silencing originally assigned to all plant microRNAs. Using Arabidopsis thaliana as our model system, here we report on both the core and auxiliary sets of machinery proteins now known to be required for both microRNA production and microRNA action in plants." @default.
- W2913372231 created "2019-02-21" @default.
- W2913372231 creator A5004871309 @default.
- W2913372231 creator A5044446665 @default.
- W2913372231 creator A5064075468 @default.
- W2913372231 date "2019-01-01" @default.
- W2913372231 modified "2023-09-27" @default.
- W2913372231 title "The Plant microRNA Pathway: The Production and Action Stages" @default.
- W2913372231 cites W1534114767 @default.
- W2913372231 cites W1560595552 @default.
- W2913372231 cites W1952594807 @default.
- W2913372231 cites W1963743411 @default.
- W2913372231 cites W1964552017 @default.
- W2913372231 cites W1968948510 @default.
- W2913372231 cites W1972281297 @default.
- W2913372231 cites W1972999456 @default.
- W2913372231 cites W1973726689 @default.
- W2913372231 cites W1975763913 @default.
- W2913372231 cites W1976303288 @default.
- W2913372231 cites W1980744469 @default.
- W2913372231 cites W1980998270 @default.
- W2913372231 cites W1986352294 @default.
- W2913372231 cites W1988801159 @default.
- W2913372231 cites W1991515074 @default.
- W2913372231 cites W1999828857 @default.
- W2913372231 cites W2008057145 @default.
- W2913372231 cites W2010541841 @default.
- W2913372231 cites W2011518477 @default.
- W2913372231 cites W2017373213 @default.
- W2913372231 cites W2018537418 @default.
- W2913372231 cites W2018899540 @default.
- W2913372231 cites W2019739870 @default.
- W2913372231 cites W2019993012 @default.
- W2913372231 cites W2025289509 @default.
- W2913372231 cites W2030989926 @default.
- W2913372231 cites W2035340311 @default.
- W2913372231 cites W2038146075 @default.
- W2913372231 cites W2038863428 @default.
- W2913372231 cites W2039305331 @default.
- W2913372231 cites W2041766861 @default.
- W2913372231 cites W2043686232 @default.
- W2913372231 cites W2045846885 @default.
- W2913372231 cites W2047024411 @default.
- W2913372231 cites W2047937385 @default.
- W2913372231 cites W2053915285 @default.
- W2913372231 cites W2054349237 @default.
- W2913372231 cites W2055378463 @default.
- W2913372231 cites W2056376913 @default.
- W2913372231 cites W2062893740 @default.
- W2913372231 cites W2067775919 @default.
- W2913372231 cites W2072017031 @default.
- W2913372231 cites W2073311353 @default.
- W2913372231 cites W2074106269 @default.
- W2913372231 cites W2075107437 @default.
- W2913372231 cites W2076290480 @default.
- W2913372231 cites W2077928332 @default.
- W2913372231 cites W2078271662 @default.
- W2913372231 cites W2083217743 @default.
- W2913372231 cites W2085833759 @default.
- W2913372231 cites W2087211197 @default.
- W2913372231 cites W2096357624 @default.
- W2913372231 cites W2096842515 @default.
- W2913372231 cites W2097605374 @default.
- W2913372231 cites W2098407761 @default.
- W2913372231 cites W2101317230 @default.
- W2913372231 cites W2106598531 @default.
- W2913372231 cites W2110755664 @default.
- W2913372231 cites W2112568073 @default.
- W2913372231 cites W2116672276 @default.
- W2913372231 cites W2117021101 @default.
- W2913372231 cites W2120843884 @default.
- W2913372231 cites W2121583611 @default.
- W2913372231 cites W2121812076 @default.
- W2913372231 cites W2122889796 @default.
- W2913372231 cites W2123846805 @default.
- W2913372231 cites W2125285877 @default.
- W2913372231 cites W2125346459 @default.
- W2913372231 cites W2126225792 @default.
- W2913372231 cites W2127198496 @default.
- W2913372231 cites W2130435778 @default.
- W2913372231 cites W2133961942 @default.
- W2913372231 cites W2135101102 @default.
- W2913372231 cites W2136156198 @default.
- W2913372231 cites W2136405950 @default.
- W2913372231 cites W2137672602 @default.
- W2913372231 cites W2137915351 @default.
- W2913372231 cites W2139564786 @default.
- W2913372231 cites W2140415861 @default.
- W2913372231 cites W2142214917 @default.
- W2913372231 cites W2143593801 @default.
- W2913372231 cites W2144634693 @default.
- W2913372231 cites W2147719519 @default.
- W2913372231 cites W2147860548 @default.
- W2913372231 cites W2149149643 @default.
- W2913372231 cites W2150273317 @default.
- W2913372231 cites W2154283725 @default.
- W2913372231 cites W2156257668 @default.
- W2913372231 cites W2157542060 @default.