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- W2913419534 abstract "Phage display is a powerful technique for studying protein–ligand interactions most frequently applied to protein–protein, protein–peptide, and protein–nucleic acids interactions. The genetic code for the protein/peptide of interest is inserted in the genome of a phage and subsequently “displayed” on the surface of the viral particle as a fusion to natural coat protein. Libraries of protein/peptide variants are tested against ligand(s) of interest. Proteins/peptides binding to the specific target are selected by 3–5 rounds of affinity-driven biopanning and subsequently identified by sequencing the genome of the phages displaying them. Phage display is widely used for a selection of proteins/peptides with desired binding properties for the purpose of a broad array of therapeutic, research, and nanotechnology-related applications." @default.
- W2913419534 created "2019-02-21" @default.
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- W2913419534 date "2018-01-01" @default.
- W2913419534 modified "2023-09-27" @default.
- W2913419534 title "Phage Display" @default.
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- W2913419534 doi "https://doi.org/10.1016/b978-0-12-810514-6.00005-2" @default.
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