FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913441973> ?p ?o ?g. }

• W2913441973 endingPage "192" @default.
• W2913441973 startingPage "186" @default.
• W2913441973 abstract "Lead represents a highly prevalent metal toxicant with potential to alter human biology in lasting ways. A population segment that is particularly vulnerable to the negative consequences of lead exposure is the human fetus, as exposure events occurring before birth are linked to varied and long-ranging negative health and behavioral outcomes. An area that has yet to be addressed is the potential that lead exposure during pregnancy alters brain development even before an individual is born. Here, we combine prenatal lead exposure information extracted from newborn bloodspots with the human fetal brain functional MRI data to assess whether neural network connectivity differs between lead-exposed and lead-naïve fetuses. We found that neural connectivity patterns differed in lead-exposed and comparison groups such that fetuses that were not exposed demonstrated stronger age-related increases in cross-hemispheric connectivity, while the lead-exposed group demonstrated stronger age-related increases in posterior cingulate cortex (PCC) to lateral prefrontal cortex (PFC) connectivity. These are the first results to demonstrate metal toxicant-related alterations in human fetal neural connectivity. Remarkably, the findings point to alterations in systems that support higher-order cognitive and regulatory functions. Objectives for future work are to replicate these results in larger samples and to test the possibility that these alterations may account for significant variation in future child cognitive and behavioral outcomes." @default.
• W2913441973 created "2019-02-21" @default.
• W2913441973 creator A5007353624 @default.
• W2913441973 creator A5012577804 @default.
• W2913441973 creator A5018461942 @default.
• W2913441973 creator A5019259188 @default.
• W2913441973 creator A5038719346 @default.
• W2913441973 creator A5050658735 @default.
• W2913441973 creator A5077759235 @default.
• W2913441973 creator A5091766669 @default.
• W2913441973 date "2019-05-01" @default.
• W2913441973 modified "2023-10-17" @default.
• W2913441973 title "Prenatal lead exposure impacts cross-hemispheric and long-range connectivity in the human fetal brain" @default.
• W2913441973 cites W1760829075 @default.
• W2913441973 cites W1965325756 @default.
• W2913441973 cites W1969304348 @default.
• W2913441973 cites W1976982012 @default.
• W2913441973 cites W1979370081 @default.
• W2913441973 cites W1997298866 @default.
• W2913441973 cites W1998148588 @default.
• W2913441973 cites W2001711670 @default.
• W2913441973 cites W2004874491 @default.
• W2913441973 cites W2006096283 @default.
• W2913441973 cites W2009494091 @default.
• W2913441973 cites W2016248307 @default.
• W2913441973 cites W2017176198 @default.
• W2913441973 cites W2025217523 @default.
• W2913441973 cites W2030993584 @default.
• W2913441973 cites W2033970892 @default.
• W2913441973 cites W2034945096 @default.
• W2913441973 cites W2038375113 @default.
• W2913441973 cites W2049095415 @default.
• W2913441973 cites W2049791931 @default.
• W2913441973 cites W2052679704 @default.
• W2913441973 cites W2057236586 @default.
• W2913441973 cites W2060980400 @default.
• W2913441973 cites W2070581948 @default.
• W2913441973 cites W2072465636 @default.
• W2913441973 cites W2082714165 @default.
• W2913441973 cites W2091575507 @default.
• W2913441973 cites W2094437093 @default.
• W2913441973 cites W2097101805 @default.
• W2913441973 cites W2100756519 @default.
• W2913441973 cites W2100980426 @default.
• W2913441973 cites W2104016179 @default.
• W2913441973 cites W2105722208 @default.
• W2913441973 cites W2106396500 @default.
• W2913441973 cites W2109840034 @default.
• W2913441973 cites W2115687188 @default.
• W2913441973 cites W2119422439 @default.
• W2913441973 cites W2119515241 @default.
• W2913441973 cites W2121236251 @default.
• W2913441973 cites W2122457251 @default.
• W2913441973 cites W2130010412 @default.
• W2913441973 cites W2131181615 @default.
• W2913441973 cites W2139861718 @default.
• W2913441973 cites W2150472995 @default.
• W2913441973 cites W2152274187 @default.
• W2913441973 cites W2152848683 @default.
• W2913441973 cites W2154395565 @default.
• W2913441973 cites W2164998314 @default.
• W2913441973 cites W2174599020 @default.
• W2913441973 cites W2192936979 @default.
• W2913441973 cites W2329839411 @default.
• W2913441973 cites W2411473379 @default.
• W2913441973 cites W2547584930 @default.
• W2913441973 cites W2569374490 @default.
• W2913441973 cites W2570687821 @default.
• W2913441973 cites W2754770663 @default.
• W2913441973 cites W2772365112 @default.
• W2913441973 cites W2792845223 @default.
• W2913441973 cites W2793043361 @default.
• W2913441973 cites W2886085041 @default.
• W2913441973 cites W2888665793 @default.
• W2913441973 cites W2891215035 @default.
• W2913441973 cites W2894604762 @default.
• W2913441973 cites W2988356887 @default.
• W2913441973 cites W71257574 @default.
• W2913441973 doi "https://doi.org/10.1016/j.neuroimage.2019.02.017" @default.
• W2913441973 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6451829" @default.
• W2913441973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30739062" @default.
• W2913441973 hasPublicationYear "2019" @default.
• W2913441973 type Work @default.
• W2913441973 sameAs 2913441973 @default.
• W2913441973 citedByCount "49" @default.
• W2913441973 countsByYear W29134419732019 @default.
• W2913441973 countsByYear W29134419732020 @default.
• W2913441973 countsByYear W29134419732021 @default.
• W2913441973 countsByYear W29134419732022 @default.
• W2913441973 countsByYear W29134419732023 @default.
• W2913441973 crossrefType "journal-article" @default.
• W2913441973 hasAuthorship W2913441973A5007353624 @default.
• W2913441973 hasAuthorship W2913441973A5012577804 @default.
• W2913441973 hasAuthorship W2913441973A5018461942 @default.
• W2913441973 hasAuthorship W2913441973A5019259188 @default.
• W2913441973 hasAuthorship W2913441973A5038719346 @default.
• W2913441973 hasAuthorship W2913441973A5050658735 @default.
• W2913441973 hasAuthorship W2913441973A5077759235 @default.

• next