Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913492810> ?p ?o ?g. }
- W2913492810 endingPage "1219" @default.
- W2913492810 startingPage "1195" @default.
- W2913492810 abstract "ABSTRACT The production of highly specialized spermatozoa from undifferentiated spermatogonia is a strictly organized and programmed process requiring extensive restructuring of the entire cell. One of the most remarkable cellular transformations accompanying the various phases of spermatogenesis is the profound remodelling of the nuclear architecture, in which the nuclear envelope (NE) seems to be crucially involved. In recent years, several proteins from the distinct layers forming the NE (i.e. the inner and outer nuclear membranes as well as the nuclear lamina) have been associated with meiosis and/or spermiogenesis in different mammalian species. Among these are A‐ and B‐type lamins, Dpy‐19‐like protein 2 (DPY19L2), lamin B receptor (LBR), lamina‐associated polypeptide 1 (LAP1), LAP2/emerin/MAN1 (LEM) domain‐containing proteins, spermatogenesis‐associated 46 (SPATA46) and diverse elements of the linker of nucleoskeleton and cytoskeleton (LINC) complex, namely Sad‐1/UNC‐84 homology (SUN) and Klarsicht/ANC‐1/Syne‐1 homology (KASH) domain‐containing proteins. Herein, we summarize the current state of the art on the cellular and subcellular distribution of NE proteins expressed during mammalian spermatogenesis, and discuss the latest research developments regarding their testis‐specific functions. This review provides a comprehensive and innovative overview of the NE network as a regulatory platform and as an essential determinant of efficient meiotic chromosome recombination as well as spermiogenesis‐associated nuclear remodelling and differentiation in mammalian male germline cells. Thus, this review provides important novel insights on the biological relevance of NE proteins for male fertility." @default.
- W2913492810 created "2019-02-21" @default.
- W2913492810 creator A5036228122 @default.
- W2913492810 creator A5036907418 @default.
- W2913492810 creator A5038669912 @default.
- W2913492810 creator A5043916529 @default.
- W2913492810 creator A5088407760 @default.
- W2913492810 date "2019-01-31" @default.
- W2913492810 modified "2023-10-14" @default.
- W2913492810 title "Nuclear envelope dynamics during mammalian spermatogenesis: new insights on male fertility" @default.
- W2913492810 cites W1119021472 @default.
- W2913492810 cites W1501769922 @default.
- W2913492810 cites W1514903902 @default.
- W2913492810 cites W1558471866 @default.
- W2913492810 cites W1794940875 @default.
- W2913492810 cites W1814020122 @default.
- W2913492810 cites W1886561247 @default.
- W2913492810 cites W1964666836 @default.
- W2913492810 cites W1964878938 @default.
- W2913492810 cites W1967964558 @default.
- W2913492810 cites W1968388559 @default.
- W2913492810 cites W1969901238 @default.
- W2913492810 cites W1971712282 @default.
- W2913492810 cites W1974862758 @default.
- W2913492810 cites W1979635135 @default.
- W2913492810 cites W1990850819 @default.
- W2913492810 cites W1997727959 @default.
- W2913492810 cites W20054081 @default.
- W2913492810 cites W2010335932 @default.
- W2913492810 cites W2014615320 @default.
- W2913492810 cites W2016270716 @default.
- W2913492810 cites W2016619116 @default.
- W2913492810 cites W2018258698 @default.
- W2913492810 cites W2021688302 @default.
- W2913492810 cites W2022455910 @default.
- W2913492810 cites W2024847424 @default.
- W2913492810 cites W2026657484 @default.
- W2913492810 cites W2037485665 @default.
- W2913492810 cites W2038761244 @default.
- W2913492810 cites W2043485308 @default.
- W2913492810 cites W2043846400 @default.
- W2913492810 cites W2058043829 @default.
- W2913492810 cites W2065259650 @default.
- W2913492810 cites W2065776621 @default.
- W2913492810 cites W2074454264 @default.
- W2913492810 cites W2074793941 @default.
- W2913492810 cites W2077254683 @default.
- W2913492810 cites W2078596128 @default.
- W2913492810 cites W2079003718 @default.
- W2913492810 cites W2079396138 @default.
- W2913492810 cites W2083445028 @default.
- W2913492810 cites W2089334040 @default.
- W2913492810 cites W2090147884 @default.
- W2913492810 cites W2091376022 @default.
- W2913492810 cites W2093966606 @default.
- W2913492810 cites W2098955066 @default.
- W2913492810 cites W2099224756 @default.
- W2913492810 cites W2101700342 @default.
- W2913492810 cites W2118117928 @default.
- W2913492810 cites W2118962346 @default.
- W2913492810 cites W2122880658 @default.
- W2913492810 cites W2123283684 @default.
- W2913492810 cites W2125307667 @default.
- W2913492810 cites W2127394968 @default.
- W2913492810 cites W2127508075 @default.
- W2913492810 cites W2130388722 @default.
- W2913492810 cites W2131840166 @default.
- W2913492810 cites W2133993320 @default.
- W2913492810 cites W2136829948 @default.
- W2913492810 cites W2138932970 @default.
- W2913492810 cites W2140915850 @default.
- W2913492810 cites W2143771854 @default.
- W2913492810 cites W2149063789 @default.
- W2913492810 cites W2153605484 @default.
- W2913492810 cites W2162493325 @default.
- W2913492810 cites W2168480092 @default.
- W2913492810 cites W2169887402 @default.
- W2913492810 cites W2171432112 @default.
- W2913492810 cites W2203098383 @default.
- W2913492810 cites W2233283131 @default.
- W2913492810 cites W2260231534 @default.
- W2913492810 cites W2277698104 @default.
- W2913492810 cites W2314179564 @default.
- W2913492810 cites W2322474005 @default.
- W2913492810 cites W2346957178 @default.
- W2913492810 cites W2414515586 @default.
- W2913492810 cites W2497148028 @default.
- W2913492810 cites W2518975446 @default.
- W2913492810 cites W2533955468 @default.
- W2913492810 cites W2534142692 @default.
- W2913492810 cites W2581101120 @default.
- W2913492810 cites W2604815929 @default.
- W2913492810 cites W2730995483 @default.
- W2913492810 cites W2734313640 @default.
- W2913492810 cites W2743817551 @default.
- W2913492810 cites W2752223362 @default.
- W2913492810 cites W2758706445 @default.
- W2913492810 cites W2770559682 @default.