FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913644292> ?p ?o ?g. }

• W2913644292 endingPage "S1532" @default.
• W2913644292 startingPage "S1532" @default.
• W2913644292 abstract "Introduction: Hyperkalemia, although a common electrolyte abnormality, poses a grave danger in causing cardiac arrhythmias and possibly death if not corrected. Sodium polystyrene sulfonate (Kayexalate) plays a role in the excretion of potassium from the gastrointestinal tract. Since its approval in 1958, Kayexalate's efficacy has been debatable and very few cases of colonic and ileal necrosis were reported. We report a case of an 80-year-old female with hyperkalemia who was treated with Kayexalate and developed colonic ischemia. Case: An 80-year-old -female with chronic kidney disease stage V and coronary artery disease presented for worsening bilateral lower extremity swelling and decreased exercise tolerance. Patient was admitted for congestive heart failure exacerbation. During the stay, she developed hyperkalemia with potassium of 6.6 mmol/L for which she was managed with oral Kayexalate. Subsequently, the patient complained of abdominal pain with bright red blood in the stool. Vitals were normal. On physical examination, abdomen was distended, and diffusely tender with guarding. Laboratory results showed white cell count of 29.4 K/cmm, hemoglobin 8.9 gm/dl and lactic acid of 3.8. Computed tomography (CT) scan of abdomen and pelvis demonstrated wall thickening, pneumatosis coli and adjacent fat stranding at the transverse colon [Figure 1]. Colonoscopy revealed lumen obstructing clot in the mid transverse colon with adjacent unhealthy mucosa which which was bleeding upon contact. Scope could not be advanced safely past the large clot [Figure 2]. Patient was managed conservatively with significant improvement eventually.Figure: CT revealing wall thickening and pneumatosis coli at the distal ascending to proximal transverse colon (red arrow).Figure: Colonoscopy showing signs of active bleeding in the transverse colon.Discussion: Sodium polystyrene sulfate is a cation exchange resin, given orally or as an enema for treatment of hyperkalemia. Kayexalate induced colonic necrosis may occur as early as a few hours to many days after administration. Patients present with complaints of abdominal pain, nausea, diarrhea and/or rectal bleeding. The diagnosis is often confirmed with colonoscopy and histopathology of biopsy specimen. Histology may show angulated crystals of sodium polystyrene sulfate in segments of mucosal erosions, ulcerations or necrosis. In conclusion, with increasing numbers of patients with end stage kidney disease, hyperkalemia remains an ever common condition encountered by clinicians. Therefore, clinicians must maintain a low threshold of suspicion for the rare but dire complication of colonic necrosis induced by kayexalate." @default.
• W2913644292 created "2019-02-21" @default.
• W2913644292 creator A5017302492 @default.
• W2913644292 creator A5019120785 @default.
• W2913644292 creator A5032046743 @default.
• W2913644292 date "2017-10-01" @default.
• W2913644292 modified "2023-09-26" @default.
• W2913644292 title "Kayexalate-Induced Ischemic Colitis: A Rare Entity" @default.
• W2913644292 doi "https://doi.org/10.14309/00000434-201710001-02857" @default.
• W2913644292 hasPublicationYear "2017" @default.
• W2913644292 type Work @default.
• W2913644292 sameAs 2913644292 @default.
• W2913644292 citedByCount "0" @default.
• W2913644292 crossrefType "journal-article" @default.
• W2913644292 hasAuthorship W2913644292A5017302492 @default.
• W2913644292 hasAuthorship W2913644292A5019120785 @default.
• W2913644292 hasAuthorship W2913644292A5032046743 @default.
• W2913644292 hasConcept C121608353 @default.
• W2913644292 hasConcept C126322002 @default.
• W2913644292 hasConcept C141071460 @default.
• W2913644292 hasConcept C164705383 @default.
• W2913644292 hasConcept C2777807078 @default.
• W2913644292 hasConcept C2778198053 @default.
• W2913644292 hasConcept C2778435480 @default.
• W2913644292 hasConcept C2779983558 @default.
• W2913644292 hasConcept C2780243291 @default.
• W2913644292 hasConcept C2780955771 @default.
• W2913644292 hasConcept C526805850 @default.
• W2913644292 hasConcept C71924100 @default.
• W2913644292 hasConcept C90924648 @default.
• W2913644292 hasConceptScore W2913644292C121608353 @default.
• W2913644292 hasConceptScore W2913644292C126322002 @default.
• W2913644292 hasConceptScore W2913644292C141071460 @default.
• W2913644292 hasConceptScore W2913644292C164705383 @default.
• W2913644292 hasConceptScore W2913644292C2777807078 @default.
• W2913644292 hasConceptScore W2913644292C2778198053 @default.
• W2913644292 hasConceptScore W2913644292C2778435480 @default.
• W2913644292 hasConceptScore W2913644292C2779983558 @default.
• W2913644292 hasConceptScore W2913644292C2780243291 @default.
• W2913644292 hasConceptScore W2913644292C2780955771 @default.
• W2913644292 hasConceptScore W2913644292C526805850 @default.
• W2913644292 hasConceptScore W2913644292C71924100 @default.
• W2913644292 hasConceptScore W2913644292C90924648 @default.
• W2913644292 hasLocation W29136442921 @default.
• W2913644292 hasOpenAccess W2913644292 @default.
• W2913644292 hasPrimaryLocation W29136442921 @default.
• W2913644292 hasRelatedWork W200457744 @default.
• W2913644292 hasRelatedWork W2008727322 @default.
• W2913644292 hasRelatedWork W2029679167 @default.
• W2913644292 hasRelatedWork W2125804349 @default.
• W2913644292 hasRelatedWork W2384196439 @default.
• W2913644292 hasRelatedWork W2409826980 @default.
• W2913644292 hasRelatedWork W2548631041 @default.
• W2913644292 hasRelatedWork W2877440243 @default.
• W2913644292 hasRelatedWork W3020811650 @default.
• W2913644292 hasRelatedWork W97426746 @default.
• W2913644292 hasVolume "112" @default.
• W2913644292 isParatext "false" @default.
• W2913644292 isRetracted "false" @default.
• W2913644292 magId "2913644292" @default.
• W2913644292 workType "article" @default.