Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913661514> ?p ?o ?g. }
- W2913661514 endingPage "3341" @default.
- W2913661514 startingPage "3336" @default.
- W2913661514 abstract "Many mitochondria-related diseases are associated with the mutation of mitochondrial DNA (mtDNA). Therefore, visualizing its dynamics in live cells is essential for the understanding of the function of mtDNA transcription and translation. By employing carbazole as the framework and designing a module for DNA minor-groove binding, here we have developed a novel fluorescent probe with a large Stokes shift (λab = 480 nm and λem = 620 nm), CNQ, for mtDNA detection and visualization. It is almost nonfluorescent in PBS buffer and exhibits 182-fold enhancement in fluorescence within 20 s after the application of mtDNA in the solution, with a detection limit of 55.1 μg/L. Using dual-color Hessian-structured illumination microscopy, we have demonstrated that CNQ-labeled mtDNA structures are distinct from those labeled by TFAM-EGFP. Finally, we have used two-photon confocal scanning microscopy (λex = 850 nm) to monitor the nondestructive doxorubicin-induced mtDNA damage in live cells." @default.
- W2913661514 created "2019-02-21" @default.
- W2913661514 creator A5014458578 @default.
- W2913661514 creator A5031603333 @default.
- W2913661514 creator A5032901042 @default.
- W2913661514 creator A5046132833 @default.
- W2913661514 creator A5049304171 @default.
- W2913661514 creator A5073547897 @default.
- W2913661514 creator A5087949054 @default.
- W2913661514 date "2019-02-06" @default.
- W2913661514 modified "2023-10-17" @default.
- W2913661514 title "An Off–On Two-Photon Carbazole-Based Fluorescent Probe: Highly Targeting and Super-Resolution Imaging of mtDNA" @default.
- W2913661514 cites W1968197570 @default.
- W2913661514 cites W1971369889 @default.
- W2913661514 cites W1975881941 @default.
- W2913661514 cites W1988888878 @default.
- W2913661514 cites W1988915590 @default.
- W2913661514 cites W1993278949 @default.
- W2913661514 cites W1993281630 @default.
- W2913661514 cites W1994640446 @default.
- W2913661514 cites W2003425904 @default.
- W2913661514 cites W2021338378 @default.
- W2913661514 cites W2028364813 @default.
- W2913661514 cites W2028434032 @default.
- W2913661514 cites W2030637794 @default.
- W2913661514 cites W2031610614 @default.
- W2913661514 cites W2039152232 @default.
- W2913661514 cites W2067468321 @default.
- W2913661514 cites W2073722067 @default.
- W2913661514 cites W2094462270 @default.
- W2913661514 cites W2095335747 @default.
- W2913661514 cites W2106674366 @default.
- W2913661514 cites W2109291482 @default.
- W2913661514 cites W2121503635 @default.
- W2913661514 cites W2128525472 @default.
- W2913661514 cites W2140751228 @default.
- W2913661514 cites W2144119801 @default.
- W2913661514 cites W2149612795 @default.
- W2913661514 cites W2150705960 @default.
- W2913661514 cites W2154414424 @default.
- W2913661514 cites W2166664098 @default.
- W2913661514 cites W2171062511 @default.
- W2913661514 cites W2215157730 @default.
- W2913661514 cites W2315080745 @default.
- W2913661514 cites W2316829517 @default.
- W2913661514 cites W2321739813 @default.
- W2913661514 cites W2355866668 @default.
- W2913661514 cites W2409276767 @default.
- W2913661514 cites W2514833799 @default.
- W2913661514 cites W2560534594 @default.
- W2913661514 cites W2592037468 @default.
- W2913661514 cites W2739693349 @default.
- W2913661514 cites W2800516378 @default.
- W2913661514 cites W2884650347 @default.
- W2913661514 cites W2891297904 @default.
- W2913661514 cites W4313452448 @default.
- W2913661514 cites W4376848339 @default.
- W2913661514 doi "https://doi.org/10.1021/acs.analchem.8b04418" @default.
- W2913661514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30724069" @default.
- W2913661514 hasPublicationYear "2019" @default.
- W2913661514 type Work @default.
- W2913661514 sameAs 2913661514 @default.
- W2913661514 citedByCount "27" @default.
- W2913661514 countsByYear W29136615142019 @default.
- W2913661514 countsByYear W29136615142020 @default.
- W2913661514 countsByYear W29136615142021 @default.
- W2913661514 countsByYear W29136615142022 @default.
- W2913661514 countsByYear W29136615142023 @default.
- W2913661514 crossrefType "journal-article" @default.
- W2913661514 hasAuthorship W2913661514A5014458578 @default.
- W2913661514 hasAuthorship W2913661514A5031603333 @default.
- W2913661514 hasAuthorship W2913661514A5032901042 @default.
- W2913661514 hasAuthorship W2913661514A5046132833 @default.
- W2913661514 hasAuthorship W2913661514A5049304171 @default.
- W2913661514 hasAuthorship W2913661514A5073547897 @default.
- W2913661514 hasAuthorship W2913661514A5087949054 @default.
- W2913661514 hasConcept C104317684 @default.
- W2913661514 hasConcept C120665830 @default.
- W2913661514 hasConcept C121332964 @default.
- W2913661514 hasConcept C12554922 @default.
- W2913661514 hasConcept C136009344 @default.
- W2913661514 hasConcept C147080431 @default.
- W2913661514 hasConcept C1491633281 @default.
- W2913661514 hasConcept C153911025 @default.
- W2913661514 hasConcept C15526883 @default.
- W2913661514 hasConcept C169274487 @default.
- W2913661514 hasConcept C169415338 @default.
- W2913661514 hasConcept C185592680 @default.
- W2913661514 hasConcept C24586158 @default.
- W2913661514 hasConcept C2779178360 @default.
- W2913661514 hasConcept C55493867 @default.
- W2913661514 hasConcept C86803240 @default.
- W2913661514 hasConcept C91881484 @default.
- W2913661514 hasConcept C95444343 @default.
- W2913661514 hasConceptScore W2913661514C104317684 @default.
- W2913661514 hasConceptScore W2913661514C120665830 @default.
- W2913661514 hasConceptScore W2913661514C121332964 @default.
- W2913661514 hasConceptScore W2913661514C12554922 @default.