Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913699685> ?p ?o ?g. }
- W2913699685 endingPage "1437" @default.
- W2913699685 startingPage "1429" @default.
- W2913699685 abstract "DNA methylation (DNAm) silences gene expression and may play a role in immune dysregulation that is characteristic of adolescent/young adult Hodgkin lymphoma (AYAHL). We used the Infinium HumanMethylation27 BeadChip to quantify DNAm in blood (N = 9 pairs, mean age 57.4 y) or saliva (N = 36 pairs, mean age 50.0 y) from long-term AYAHL survivors and their unaffected co-twins. Epigenetic aging (DNAm age) was calculated using previously described methods and compared between survivors and co-twins using paired t-tests and analyses were stratified by sample type, histology, sex, age at sample collection and time since diagnosis. Differences in blood DNAm age were observed between survivors and unaffected co-twins (64.1 vs. 61.3 years, respectively, p = .04), especially in females (p = .01); no differences in saliva DNAm age were observed. Survivors and co-twins had 74 (in blood DNA) and 6 (in saliva DNA) differentially methylated loci. Our results suggest persistent epigenetic aging in AYAHL survivors long after HL cure." @default.
- W2913699685 created "2019-02-21" @default.
- W2913699685 creator A5000192581 @default.
- W2913699685 creator A5007768066 @default.
- W2913699685 creator A5020544186 @default.
- W2913699685 creator A5029377806 @default.
- W2913699685 creator A5040907882 @default.
- W2913699685 creator A5042241049 @default.
- W2913699685 creator A5044526750 @default.
- W2913699685 creator A5045179361 @default.
- W2913699685 creator A5064179551 @default.
- W2913699685 creator A5067821687 @default.
- W2913699685 creator A5084471463 @default.
- W2913699685 date "2019-01-22" @default.
- W2913699685 modified "2023-10-06" @default.
- W2913699685 title "DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin" @default.
- W2913699685 cites W1634084408 @default.
- W2913699685 cites W1946824863 @default.
- W2913699685 cites W1974047233 @default.
- W2913699685 cites W1978449568 @default.
- W2913699685 cites W1979808430 @default.
- W2913699685 cites W1985512844 @default.
- W2913699685 cites W1998090590 @default.
- W2913699685 cites W2004053519 @default.
- W2913699685 cites W2004078197 @default.
- W2913699685 cites W2006934296 @default.
- W2913699685 cites W2023948557 @default.
- W2913699685 cites W2027786624 @default.
- W2913699685 cites W2032602115 @default.
- W2913699685 cites W2032938314 @default.
- W2913699685 cites W2045627979 @default.
- W2913699685 cites W2046741533 @default.
- W2913699685 cites W2053856108 @default.
- W2913699685 cites W2057260087 @default.
- W2913699685 cites W2057629675 @default.
- W2913699685 cites W2060057102 @default.
- W2913699685 cites W2066571531 @default.
- W2913699685 cites W2083514525 @default.
- W2913699685 cites W2086874336 @default.
- W2913699685 cites W2087581509 @default.
- W2913699685 cites W2092204393 @default.
- W2913699685 cites W2096330673 @default.
- W2913699685 cites W2100931047 @default.
- W2913699685 cites W2106269208 @default.
- W2913699685 cites W2110065044 @default.
- W2913699685 cites W2113637769 @default.
- W2913699685 cites W2113649341 @default.
- W2913699685 cites W2116536643 @default.
- W2913699685 cites W2118385502 @default.
- W2913699685 cites W2118495846 @default.
- W2913699685 cites W2120675173 @default.
- W2913699685 cites W2121676620 @default.
- W2913699685 cites W2124770101 @default.
- W2913699685 cites W2132229447 @default.
- W2913699685 cites W2148801868 @default.
- W2913699685 cites W2159536887 @default.
- W2913699685 cites W2169556367 @default.
- W2913699685 cites W2255969727 @default.
- W2913699685 cites W2265071267 @default.
- W2913699685 cites W2310337733 @default.
- W2913699685 cites W2327007930 @default.
- W2913699685 cites W2416801689 @default.
- W2913699685 cites W2421283105 @default.
- W2913699685 cites W2505539351 @default.
- W2913699685 cites W2523368390 @default.
- W2913699685 cites W2728959095 @default.
- W2913699685 cites W2773327522 @default.
- W2913699685 cites W2776277657 @default.
- W2913699685 cites W2777353230 @default.
- W2913699685 cites W4234771680 @default.
- W2913699685 cites W4254512323 @default.
- W2913699685 doi "https://doi.org/10.1080/10428194.2018.1533128" @default.
- W2913699685 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7781082" @default.
- W2913699685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30668190" @default.
- W2913699685 hasPublicationYear "2019" @default.
- W2913699685 type Work @default.
- W2913699685 sameAs 2913699685 @default.
- W2913699685 citedByCount "11" @default.
- W2913699685 countsByYear W29136996852019 @default.
- W2913699685 countsByYear W29136996852020 @default.
- W2913699685 countsByYear W29136996852021 @default.
- W2913699685 countsByYear W29136996852022 @default.
- W2913699685 crossrefType "journal-article" @default.
- W2913699685 hasAuthorship W2913699685A5000192581 @default.
- W2913699685 hasAuthorship W2913699685A5007768066 @default.
- W2913699685 hasAuthorship W2913699685A5020544186 @default.
- W2913699685 hasAuthorship W2913699685A5029377806 @default.
- W2913699685 hasAuthorship W2913699685A5040907882 @default.
- W2913699685 hasAuthorship W2913699685A5042241049 @default.
- W2913699685 hasAuthorship W2913699685A5044526750 @default.
- W2913699685 hasAuthorship W2913699685A5045179361 @default.
- W2913699685 hasAuthorship W2913699685A5064179551 @default.
- W2913699685 hasAuthorship W2913699685A5067821687 @default.
- W2913699685 hasAuthorship W2913699685A5084471463 @default.
- W2913699685 hasBestOaLocation W29136996852 @default.
- W2913699685 hasConcept C104317684 @default.
- W2913699685 hasConcept C126322002 @default.
- W2913699685 hasConcept C143998085 @default.