FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913715211> ?p ?o ?g. }

• W2913715211 endingPage "2199" @default.
• W2913715211 startingPage "2185" @default.
• W2913715211 abstract "Key points To uncover the synaptic profile of Renshaw inhibition on motoneurons, we stimulated thick motor axons and recorded from voluntarily‐activated motor units. Stimuli generated a direct motor response on the whole muscle and an inhibitory response in active motor units. We have estimated the profile of Renshaw inhibition indirectly using the response of motor unit discharge rates to the stimulus. We have put forward a method of extrapolation that may be used to determine genuine synaptic potentials as they develop on motoneurons. These optimized techniques can be used in research and in clinics to fully appreciate Renshaw cell function in various neurological disorders. Abstract Although Renshaw inhibition (RI) has been extensively studied for decades, its precise role in motor control is yet to be discovered. One of the main handicaps is a lack of reliable methods for studying RI in conscious human subjects. We stimulated the lowest electrical threshold motor axons (thickest axons) in the tibial nerve and analysed the stimulus‐correlated changes in discharge of voluntarily recruited low‐threshold single motor units (SMUs) from the soleus muscle. In total, 54 distinct SMUs from 12 subjects were analysed. Stimuli that generated only the direct motor response (M‐only) on surface electromyography induced an inhibitory response in the low‐threshold SMUs. Because the properties of RI had to be estimated indirectly using the background discharge rate of SMUs, its profile varied with the discharge rate of the SMU. The duration of RI was found to be inversely proportional to the discharge rate of SMUs. Using this important finding, we have developed a method of extrapolation for estimating RI as it develops on motoneurons in the spinal cord. The frequency methods indicated that the duration of RI was between 30 and 40 ms depending on the background firing rate of the units, and the extrapolation indicated that RI on silent motoneurons was ∼55 ms. The present study establishes a novel methodology for studying RI in human subjects and hence may serve as a tool for improving our understanding of the involvement of RI in human motor control." @default.
• W2913715211 created "2019-02-21" @default.
• W2913715211 creator A5014061933 @default.
• W2913715211 creator A5016595523 @default.
• W2913715211 creator A5028499640 @default.
• W2913715211 creator A5036380136 @default.
• W2913715211 creator A5052132372 @default.
• W2913715211 date "2019-02-06" @default.
• W2913715211 modified "2023-10-16" @default.
• W2913715211 title "Motor units as tools to evaluate profile of human Renshaw inhibition" @default.
• W2913715211 cites W1895345041 @default.
• W2913715211 cites W1966728583 @default.
• W2913715211 cites W1966764948 @default.
• W2913715211 cites W1974967668 @default.
• W2913715211 cites W1976442426 @default.
• W2913715211 cites W1976784119 @default.
• W2913715211 cites W1980349290 @default.
• W2913715211 cites W1981030777 @default.
• W2913715211 cites W1985986127 @default.
• W2913715211 cites W1987737208 @default.
• W2913715211 cites W1996126631 @default.
• W2913715211 cites W1999947450 @default.
• W2913715211 cites W2008272581 @default.
• W2913715211 cites W2013684097 @default.
• W2913715211 cites W2016598174 @default.
• W2913715211 cites W2017432544 @default.
• W2913715211 cites W2023618174 @default.
• W2913715211 cites W2023664224 @default.
• W2913715211 cites W2028747642 @default.
• W2913715211 cites W2031657838 @default.
• W2913715211 cites W2036587861 @default.
• W2913715211 cites W2039127645 @default.
• W2913715211 cites W2044909239 @default.
• W2913715211 cites W2046770323 @default.
• W2913715211 cites W2063801516 @default.
• W2913715211 cites W2068319099 @default.
• W2913715211 cites W2073929966 @default.
• W2913715211 cites W2075947022 @default.
• W2913715211 cites W2079736230 @default.
• W2913715211 cites W2080044980 @default.
• W2913715211 cites W2080754372 @default.
• W2913715211 cites W2085306742 @default.
• W2913715211 cites W2085434455 @default.
• W2913715211 cites W2087614146 @default.
• W2913715211 cites W2099578487 @default.
• W2913715211 cites W2109236622 @default.
• W2913715211 cites W2118352903 @default.
• W2913715211 cites W2118804454 @default.
• W2913715211 cites W2122416093 @default.
• W2913715211 cites W2133762721 @default.
• W2913715211 cites W2139434922 @default.
• W2913715211 cites W2142416079 @default.
• W2913715211 cites W2145460573 @default.
• W2913715211 cites W2148170017 @default.
• W2913715211 cites W2167700167 @default.
• W2913715211 cites W2170588025 @default.
• W2913715211 cites W2207052072 @default.
• W2913715211 cites W2255945889 @default.
• W2913715211 cites W2272609131 @default.
• W2913715211 cites W2276213602 @default.
• W2913715211 cites W2329410439 @default.
• W2913715211 cites W2409015817 @default.
• W2913715211 cites W2576466194 @default.
• W2913715211 cites W2625450543 @default.
• W2913715211 cites W2884965209 @default.
• W2913715211 doi "https://doi.org/10.1113/jp277129" @default.
• W2913715211 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6462458" @default.
• W2913715211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30673125" @default.
• W2913715211 hasPublicationYear "2019" @default.
• W2913715211 type Work @default.
• W2913715211 sameAs 2913715211 @default.
• W2913715211 citedByCount "17" @default.
• W2913715211 countsByYear W29137152112019 @default.
• W2913715211 countsByYear W29137152112020 @default.
• W2913715211 countsByYear W29137152112021 @default.
• W2913715211 countsByYear W29137152112022 @default.
• W2913715211 countsByYear W29137152112023 @default.
• W2913715211 crossrefType "journal-article" @default.
• W2913715211 hasAuthorship W2913715211A5014061933 @default.
• W2913715211 hasAuthorship W2913715211A5016595523 @default.
• W2913715211 hasAuthorship W2913715211A5028499640 @default.
• W2913715211 hasAuthorship W2913715211A5036380136 @default.
• W2913715211 hasAuthorship W2913715211A5052132372 @default.
• W2913715211 hasBestOaLocation W29137152111 @default.
• W2913715211 hasConcept C15744967 @default.
• W2913715211 hasConcept C169760540 @default.
• W2913715211 hasConcept C17077164 @default.
• W2913715211 hasConcept C173172909 @default.
• W2913715211 hasConcept C185592680 @default.
• W2913715211 hasConcept C2775912687 @default.
• W2913715211 hasConcept C2776752467 @default.
• W2913715211 hasConcept C2777515770 @default.
• W2913715211 hasConcept C2778037872 @default.
• W2913715211 hasConcept C2779918689 @default.
• W2913715211 hasConcept C2780775167 @default.
• W2913715211 hasConcept C2781425072 @default.
• W2913715211 hasConcept C542102704 @default.
• W2913715211 hasConcept C71924100 @default.

• next