Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913726436> ?p ?o ?g. }
- W2913726436 abstract "β-Adrenergic receptors (ADRBs) play a pivotal role in cardiovascular disease. Recently, genetic polymorphisms of ADRB1 and ADRB2 have been suggested to be associated with cardiovascular events and all-cause mortality in coronary artery disease (CAD) patients, but the results of relevant studies are inconsistent and controversial. Therefore, we performed a meta-analysis to investigate the association between ADRB1 and ADRB2 polymorphisms with cardiovascular events and all-cause mortality in CAD patients.The PubMed, Ovid, EMBASE, Cochrane, and CINAHL databases were searched for eligible studies published before April 2018. A total of 5495 patients from eight studies were included in our meta-analysis.We found that CAD patients harboring the ADRB2 rs1042714 Glu27 allele exhibited a positive association with cardiovascular events (risk ratio [RR] = 1.31, 95% confidence interval [CI]: 1.08-1.58, p = 0.006), but not with all-cause mortality (RR = 0.97, 95% CI: 0.70-1.35, p = 0.859), compared with patients who were Gln27 homozygotes. No other significant associations were observed between ADRB1 (rs1801252, rs1801253), ADRB2 (rs1042713, rs1800888) polymorphisms and cardiovascular events or all-cause mortality in CAD patients.This study suggests that the identified ADRB2 polymorphism could influence the outcomes of CAD patients, showing important clinical value." @default.
- W2913726436 created "2019-02-21" @default.
- W2913726436 creator A5010453309 @default.
- W2913726436 creator A5011465604 @default.
- W2913726436 creator A5024572557 @default.
- W2913726436 creator A5038965879 @default.
- W2913726436 creator A5071149622 @default.
- W2913726436 creator A5075062554 @default.
- W2913726436 creator A5078250869 @default.
- W2913726436 date "2019-02-01" @default.
- W2913726436 modified "2023-10-17" @default.
- W2913726436 title "β2-Adrenergic Receptor Gene Polymorphisms Are Associated with Cardiovascular Events But not All-Cause Mortality in Coronary Artery Disease Patients: A Meta-Analysis of Prospective Studies" @default.
- W2913726436 cites W1972742428 @default.
- W2913726436 cites W1976548266 @default.
- W2913726436 cites W1982237924 @default.
- W2913726436 cites W1989543530 @default.
- W2913726436 cites W2010078192 @default.
- W2913726436 cites W2013718542 @default.
- W2913726436 cites W2018733573 @default.
- W2913726436 cites W203613584 @default.
- W2913726436 cites W2054846740 @default.
- W2913726436 cites W2067979102 @default.
- W2913726436 cites W2094030500 @default.
- W2913726436 cites W2097726101 @default.
- W2913726436 cites W2126108223 @default.
- W2913726436 cites W2417046997 @default.
- W2913726436 cites W2418309892 @default.
- W2913726436 cites W2512614465 @default.
- W2913726436 cites W2608396585 @default.
- W2913726436 cites W2615642430 @default.
- W2913726436 doi "https://doi.org/10.1089/gtmb.2018.0153" @default.
- W2913726436 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6383583" @default.
- W2913726436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30668166" @default.
- W2913726436 hasPublicationYear "2019" @default.
- W2913726436 type Work @default.
- W2913726436 sameAs 2913726436 @default.
- W2913726436 citedByCount "6" @default.
- W2913726436 countsByYear W29137264362020 @default.
- W2913726436 countsByYear W29137264362021 @default.
- W2913726436 countsByYear W29137264362022 @default.
- W2913726436 crossrefType "journal-article" @default.
- W2913726436 hasAuthorship W2913726436A5010453309 @default.
- W2913726436 hasAuthorship W2913726436A5011465604 @default.
- W2913726436 hasAuthorship W2913726436A5024572557 @default.
- W2913726436 hasAuthorship W2913726436A5038965879 @default.
- W2913726436 hasAuthorship W2913726436A5071149622 @default.
- W2913726436 hasAuthorship W2913726436A5075062554 @default.
- W2913726436 hasAuthorship W2913726436A5078250869 @default.
- W2913726436 hasBestOaLocation W29137264361 @default.
- W2913726436 hasConcept C104317684 @default.
- W2913726436 hasConcept C126322002 @default.
- W2913726436 hasConcept C164705383 @default.
- W2913726436 hasConcept C180754005 @default.
- W2913726436 hasConcept C188816634 @default.
- W2913726436 hasConcept C2778213512 @default.
- W2913726436 hasConcept C2779134260 @default.
- W2913726436 hasConcept C29374701 @default.
- W2913726436 hasConcept C44249647 @default.
- W2913726436 hasConcept C54355233 @default.
- W2913726436 hasConcept C60644358 @default.
- W2913726436 hasConcept C71924100 @default.
- W2913726436 hasConcept C82789193 @default.
- W2913726436 hasConcept C86803240 @default.
- W2913726436 hasConcept C90924648 @default.
- W2913726436 hasConcept C95190672 @default.
- W2913726436 hasConceptScore W2913726436C104317684 @default.
- W2913726436 hasConceptScore W2913726436C126322002 @default.
- W2913726436 hasConceptScore W2913726436C164705383 @default.
- W2913726436 hasConceptScore W2913726436C180754005 @default.
- W2913726436 hasConceptScore W2913726436C188816634 @default.
- W2913726436 hasConceptScore W2913726436C2778213512 @default.
- W2913726436 hasConceptScore W2913726436C2779134260 @default.
- W2913726436 hasConceptScore W2913726436C29374701 @default.
- W2913726436 hasConceptScore W2913726436C44249647 @default.
- W2913726436 hasConceptScore W2913726436C54355233 @default.
- W2913726436 hasConceptScore W2913726436C60644358 @default.
- W2913726436 hasConceptScore W2913726436C71924100 @default.
- W2913726436 hasConceptScore W2913726436C82789193 @default.
- W2913726436 hasConceptScore W2913726436C86803240 @default.
- W2913726436 hasConceptScore W2913726436C90924648 @default.
- W2913726436 hasConceptScore W2913726436C95190672 @default.
- W2913726436 hasLocation W29137264361 @default.
- W2913726436 hasLocation W29137264362 @default.
- W2913726436 hasLocation W29137264363 @default.
- W2913726436 hasLocation W29137264364 @default.
- W2913726436 hasOpenAccess W2913726436 @default.
- W2913726436 hasPrimaryLocation W29137264361 @default.
- W2913726436 hasRelatedWork W1885119863 @default.
- W2913726436 hasRelatedWork W1975389766 @default.
- W2913726436 hasRelatedWork W2071995032 @default.
- W2913726436 hasRelatedWork W2130491029 @default.
- W2913726436 hasRelatedWork W2149818158 @default.
- W2913726436 hasRelatedWork W2318187771 @default.
- W2913726436 hasRelatedWork W2592774827 @default.
- W2913726436 hasRelatedWork W2626084264 @default.
- W2913726436 hasRelatedWork W2897397781 @default.
- W2913726436 hasRelatedWork W3141700921 @default.
- W2913726436 isParatext "false" @default.
- W2913726436 isRetracted "false" @default.
- W2913726436 magId "2913726436" @default.