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- W2913852020 abstract "Le diagnostic préimplantatoire constitue une alternative au diagnostic prénatal pour une minorité de couples à risque d'avoir un enfant atteint d'une maladie génétique grave. Cette méthode fait appel aux nouvelles techniques de biologie moléculaire (polymerase chain reaction, fluorescent in situ hybridization) permettant d'étudier le statut génétique des embryons obtenus après fécondation in vitro. Seuls les embryons sains sont transférés dans l'utérus. Il est encore trop tôt pour se prononcer sur la précision et l'innocuité de cette méthode alternative au diagnostic anténatal par choriocentèse ou amniocentèse. Pre-implantation genetic diagnosis provides an alternative to prenatal diagnosis for couples who are at risk of having an offspring with a serious genetic disorder. This novel method is based on recent molecular techniques (PCR, FISH) that allow analyzing the genetic status of embryos obtained after in vitro fertilization. Only embryos free of the genetic disorder are transferred into the uterus. It is too early to establish the safety and accuracy of pre-implantation genetic diagnosis." @default.
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- W2913852020 date "2005-08-01" @default.
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- W2913852020 title "Diagnostic préimplantatoire" @default.
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- W2913852020 doi "https://doi.org/10.1016/j.emcgo.2005.07.005" @default.
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