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- W2913982013 abstract "Objective: Evaluation of the potential of combined multivariate chemometric methods for seeking markers of lung cancer. Methods: Statistical methods such as Mann-Whitney U test, discriminant function analysis (DFA), factor analysis (FA) and artificial neural network (ANN) were applied to evaluate the obtained data from GC/MS analysis of exhaled breath. Results: The total number of compounds identified by GC/MS in human breath was equal to 88. The statistical analysis indicates seven analytes which have the highest discriminatory power. Cross validation of the obtained model shows that the sensitivity was 80% and the specificity was 91.23%, while for the test group the sensitivity and specificity were both 86.36%. Conclusion: The application of combined statistical methods allowed to reduce the number of compounds to significant ones and indicates them as markers of lung cancer." @default.
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- W2913982013 date "2019-09-01" @default.
- W2913982013 modified "2023-10-13" @default.
- W2913982013 title "Searching for selected VOCs in human breath samples as potential markers of lung cancer" @default.
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- W2913982013 doi "https://doi.org/10.1016/j.lungcan.2019.02.012" @default.
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