FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914196735> ?p ?o ?g. }

• W2914196735 abstract "Telomeres, the protective structures at the ends of chromosomes, can be shortened when individuals are exposed to stress. In some species, the enzyme telomerase is expressed in adult somatic tissues, and potentially protects or lengthens telomeres. Telomeres can be damaged by ionizing radiation and oxidative stress, although the effect of chronic exposure to elevated levels of radiation on telomere maintenance is unknown for natural populations. We quantified telomerase expression and telomere length (TL) in different tissues of the bank vole Myodes glareolus, collected from the Chernobyl Exclusion Zone, an environment heterogeneously contaminated with radionuclides, and from uncontaminated control sites elsewhere in Ukraine. Inhabiting the Chernobyl Exclusion Zone was associated with reduced TL in the liver and testis, and upregulation of telomerase in brain and liver. Thus upregulation of telomerase does not appear to associate with longer telomeres but may reflect protective functions other than telomere maintenance or an attempt to maintain shorter telomeres in a stressful environment. Tissue specific differences in the rate of telomere attrition and apparent radiosensitivity weaken the intra-individual correlation in telomere length among tissues in voles exposed to radionuclides. Our data show that ionizing radiation alters telomere homeostasis in wild animal populations in tissue specific ways." @default.
• W2914196735 created "2019-02-21" @default.
• W2914196735 creator A5004240295 @default.
• W2914196735 creator A5020642204 @default.
• W2914196735 creator A5023470931 @default.
• W2914196735 creator A5039382493 @default.
• W2914196735 creator A5049215288 @default.
• W2914196735 creator A5051233105 @default.
• W2914196735 creator A5061841244 @default.
• W2914196735 creator A5071331003 @default.
• W2914196735 creator A5085621546 @default.
• W2914196735 creator A5090558209 @default.
• W2914196735 date "2019-01-29" @default.
• W2914196735 modified "2023-10-14" @default.
• W2914196735 title "Exposure to environmental radionuclides associates with tissue-specific impacts on telomerase expression and telomere length" @default.
• W2914196735 cites W1483456062 @default.
• W2914196735 cites W1517051009 @default.
• W2914196735 cites W1536515265 @default.
• W2914196735 cites W1538980175 @default.
• W2914196735 cites W1573537587 @default.
• W2914196735 cites W1612842202 @default.
• W2914196735 cites W1959307403 @default.
• W2914196735 cites W1966432404 @default.
• W2914196735 cites W1979176867 @default.
• W2914196735 cites W1979835092 @default.
• W2914196735 cites W1984555242 @default.
• W2914196735 cites W1996465461 @default.
• W2914196735 cites W1999872096 @default.
• W2914196735 cites W2000971601 @default.
• W2914196735 cites W2002628931 @default.
• W2914196735 cites W2003754826 @default.
• W2914196735 cites W2005861857 @default.
• W2914196735 cites W2008320117 @default.
• W2914196735 cites W2013607453 @default.
• W2914196735 cites W2014231393 @default.
• W2914196735 cites W2021836517 @default.
• W2914196735 cites W2026180657 @default.
• W2914196735 cites W2028483534 @default.
• W2914196735 cites W2029456327 @default.
• W2914196735 cites W2032694449 @default.
• W2914196735 cites W2033053950 @default.
• W2914196735 cites W2035625169 @default.
• W2914196735 cites W2037086740 @default.
• W2914196735 cites W2038861500 @default.
• W2914196735 cites W2040466227 @default.
• W2914196735 cites W2045629535 @default.
• W2914196735 cites W2048269733 @default.
• W2914196735 cites W2049903344 @default.
• W2914196735 cites W2058553011 @default.
• W2914196735 cites W2059847417 @default.
• W2914196735 cites W2060955969 @default.
• W2914196735 cites W2061560102 @default.
• W2914196735 cites W2085509108 @default.
• W2914196735 cites W2089374805 @default.
• W2914196735 cites W2093473156 @default.
• W2914196735 cites W2096665151 @default.
• W2914196735 cites W2096712048 @default.
• W2914196735 cites W2097529540 @default.
• W2914196735 cites W2099249565 @default.
• W2914196735 cites W2101833973 @default.
• W2914196735 cites W2109113178 @default.
• W2914196735 cites W2116830452 @default.
• W2914196735 cites W2120254180 @default.
• W2914196735 cites W2120746465 @default.
• W2914196735 cites W2125194621 @default.
• W2914196735 cites W2127456840 @default.
• W2914196735 cites W2129264114 @default.
• W2914196735 cites W2136340969 @default.
• W2914196735 cites W2136856258 @default.
• W2914196735 cites W2139808613 @default.
• W2914196735 cites W2140895326 @default.
• W2914196735 cites W2148834367 @default.
• W2914196735 cites W2154345882 @default.
• W2914196735 cites W2155703477 @default.
• W2914196735 cites W2160621707 @default.
• W2914196735 cites W2162106012 @default.
• W2914196735 cites W2167285829 @default.
• W2914196735 cites W2167659390 @default.
• W2914196735 cites W2169581310 @default.
• W2914196735 cites W2169621456 @default.
• W2914196735 cites W2170451568 @default.
• W2914196735 cites W2175722093 @default.
• W2914196735 cites W2188794972 @default.
• W2914196735 cites W2409792925 @default.
• W2914196735 cites W2559750533 @default.
• W2914196735 cites W2777975883 @default.
• W2914196735 cites W2783285216 @default.
• W2914196735 cites W2784264737 @default.
• W2914196735 cites W2793917652 @default.
• W2914196735 cites W2797926318 @default.
• W2914196735 cites W30641342 @default.
• W2914196735 doi "https://doi.org/10.1038/s41598-018-37164-8" @default.
• W2914196735 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6351625" @default.
• W2914196735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30696885" @default.
• W2914196735 hasPublicationYear "2019" @default.
• W2914196735 type Work @default.
• W2914196735 sameAs 2914196735 @default.
• W2914196735 citedByCount "29" @default.
• W2914196735 countsByYear W29141967352019 @default.
• W2914196735 countsByYear W29141967352020 @default.

• next