Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914199140> ?p ?o ?g. }
- W2914199140 abstract "Abstract Polypeptoids synthesized from N ‐substituted glycine N ‐carboxyanhydrides (NNCAs) are widely applied in biological fields. The effect of side groups in NNCA polymerizations is a key to develop novel polypeptoids with complex topologies and constituents. In this work, density functional theory (DFT) calculations are employed to investigate the propagation of a series of alkyl substituted NNCAs with solvation model. According to both computational and experimental results, carbonyl addition is confirmed as rate determining step and steric hindrance is recognized as the major factor of low reactivity in β ‐C branched NNCAs. However, in linear and γ‐C branched case, aggregation of side groups instead of bulkiness is considered responsible for low polymerization rate." @default.
- W2914199140 created "2019-02-21" @default.
- W2914199140 creator A5049980307 @default.
- W2914199140 creator A5070838784 @default.
- W2914199140 date "2019-02-12" @default.
- W2914199140 modified "2023-10-16" @default.
- W2914199140 title "Polymerization rate difference of <i>N</i> ‐alkyl glycine NCAs: Steric hindrance or not?" @default.
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- W2914199140 doi "https://doi.org/10.1002/bip.23261" @default.
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