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- W2914229286 endingPage "567" @default.
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- W2914229286 abstract "We investigated the use of a supported silicalite-1 film (SF) as a promising coating for metallic materials used in the fabrication of prostheses. The role of carbonaceous residua present on high-temperature calcined-SF in generating singlet oxygen for future use as a sterilization method has also been addressed, and the potential genotoxicity of these residua in osteoblast-like cells has been investigated. Calcination of as-synthesized SF induced the appearance of a rather complicated mixture of aliphatic and aromatic species on its outer surface. A series of variously volatile polycyclic aromatic hydrocarbons (PAH), including naphthalene, fluorene, phenanthrene, anthracene, fluoranthene, and pyrene, were identified in micromole concentrations. Irradiation of these PAHs on calcined-SF immersed in air-saturated chloroform led to the formation of very low concentrations of singlet oxygen. However, an increased level of DNA damage was observed on calcined-SF by immunofluorescence staining of phosphorylated histone H2AX analyzed by flow cytometry." @default.
- W2914229286 created "2019-02-21" @default.
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- W2914229286 date "2019-02-14" @default.
- W2914229286 modified "2023-10-18" @default.
- W2914229286 title "The Photodynamic Properties and the Genotoxicity of Heat-Treated Silicalite-1 Films" @default.
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- W2914229286 doi "https://doi.org/10.3390/ma12040567" @default.
- W2914229286 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6416588" @default.