Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914245287> ?p ?o ?g. }
- W2914245287 abstract "Membrane bilayers of eukaryotic cells are an amalgam of lipids and proteins that distinguish organelles and compartmentalise cellular functions. The mammalian cell has evolved mechanisms to sense membrane tension or damage and respond as needed. In the case of the plasma membrane and phagosomal membrane, these bilayers act as a barrier to microorganisms and are a conduit by which the host interacts with pathogens, including fungi such as Candida, Cryptococcus, Aspergillus, or Histoplasma species. Due to their size, morphological flexibility, ability to produce long filaments, secrete pathogenicity factors, and their potential to replicate within the phagosome, fungi can assault host membranes in a variety of physical and biochemical ways. In addition, the recent discovery of a fungal pore-forming peptide toxin further highlights the importance of membrane biology in the outcomes between host and fungal cells. In this review, we discuss the apparent “stretching” of membranes as a sophisticated biological response and the role of vesicular transport in combating membrane stress and damage. We also review the known pathogenicity factors and physical properties of fungal pathogens in the context of host membranes and discuss how this may contribute to pathogenic interactions between fungal and host cells." @default.
- W2914245287 created "2019-02-21" @default.
- W2914245287 creator A5011368040 @default.
- W2914245287 creator A5026106737 @default.
- W2914245287 creator A5052508191 @default.
- W2914245287 date "2019-03-07" @default.
- W2914245287 modified "2023-09-25" @default.
- W2914245287 title "Integrity under stress: Host membrane remodelling and damage by fungal pathogens" @default.
- W2914245287 cites W1500387969 @default.
- W2914245287 cites W1535528935 @default.
- W2914245287 cites W1541663010 @default.
- W2914245287 cites W1839870563 @default.
- W2914245287 cites W1967709436 @default.
- W2914245287 cites W1984813184 @default.
- W2914245287 cites W1990172999 @default.
- W2914245287 cites W1992122154 @default.
- W2914245287 cites W1997437177 @default.
- W2914245287 cites W1999340863 @default.
- W2914245287 cites W2005629359 @default.
- W2914245287 cites W2007483105 @default.
- W2914245287 cites W2007580140 @default.
- W2914245287 cites W2008888079 @default.
- W2914245287 cites W2013686234 @default.
- W2914245287 cites W2024372419 @default.
- W2914245287 cites W2027407745 @default.
- W2914245287 cites W2029490885 @default.
- W2914245287 cites W2035155416 @default.
- W2914245287 cites W2037266934 @default.
- W2914245287 cites W2037307064 @default.
- W2914245287 cites W2041143337 @default.
- W2914245287 cites W2041463901 @default.
- W2914245287 cites W2041653279 @default.
- W2914245287 cites W2052080816 @default.
- W2914245287 cites W2053957762 @default.
- W2914245287 cites W2054868502 @default.
- W2914245287 cites W2057948698 @default.
- W2914245287 cites W2068310937 @default.
- W2914245287 cites W2068868145 @default.
- W2914245287 cites W2070265193 @default.
- W2914245287 cites W2071634550 @default.
- W2914245287 cites W2096037926 @default.
- W2914245287 cites W2100317350 @default.
- W2914245287 cites W2100918356 @default.
- W2914245287 cites W2101521088 @default.
- W2914245287 cites W2107794472 @default.
- W2914245287 cites W2109438395 @default.
- W2914245287 cites W2112216057 @default.
- W2914245287 cites W2116275559 @default.
- W2914245287 cites W2117137379 @default.
- W2914245287 cites W2119211042 @default.
- W2914245287 cites W2119409346 @default.
- W2914245287 cites W2119866943 @default.
- W2914245287 cites W2120426937 @default.
- W2914245287 cites W2126764631 @default.
- W2914245287 cites W2135766664 @default.
- W2914245287 cites W2140915719 @default.
- W2914245287 cites W2144761153 @default.
- W2914245287 cites W2153104382 @default.
- W2914245287 cites W2155762422 @default.
- W2914245287 cites W2156379593 @default.
- W2914245287 cites W2158111073 @default.
- W2914245287 cites W2158528341 @default.
- W2914245287 cites W2170755663 @default.
- W2914245287 cites W2170840506 @default.
- W2914245287 cites W2170875784 @default.
- W2914245287 cites W2225487457 @default.
- W2914245287 cites W2299762035 @default.
- W2914245287 cites W2317841819 @default.
- W2914245287 cites W2326387016 @default.
- W2914245287 cites W2329943654 @default.
- W2914245287 cites W2551648587 @default.
- W2914245287 cites W2622188456 @default.
- W2914245287 cites W2756305247 @default.
- W2914245287 cites W2767031614 @default.
- W2914245287 cites W2773257251 @default.
- W2914245287 cites W2790673148 @default.
- W2914245287 cites W2791421665 @default.
- W2914245287 cites W2796110207 @default.
- W2914245287 cites W2800526695 @default.
- W2914245287 cites W2803615589 @default.
- W2914245287 cites W2806470471 @default.
- W2914245287 cites W2807119034 @default.
- W2914245287 cites W2807227034 @default.
- W2914245287 cites W2891959956 @default.
- W2914245287 cites W2896513955 @default.
- W2914245287 cites W2951636677 @default.
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- W2914245287 doi "https://doi.org/10.1111/cmi.13016" @default.
- W2914245287 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30740852" @default.
- W2914245287 hasPublicationYear "2019" @default.
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