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- W2914301819 abstract "Enzymes of the folate de novo synthesis pathway in malaria parasites are proven antimalarial drug targets. A key precursor for folate synthesis is para-aminobenzoate (pABA). In a recent study [1] (Cell Rep. 2019;26:356-363 e4), the contributions of pABA synthesis versus salvage were re-evaluated in a rodent malaria model with knockout parasites grown in mice fed with various diets. The results imply that malaria parasites can either synthesize or salvage pABA to meet the demand for folates." @default.
- W2914301819 created "2019-02-21" @default.
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- W2914301819 date "2019-03-01" @default.
- W2914301819 modified "2023-10-16" @default.
- W2914301819 title "para-Aminobenzoate Synthesis versus Salvage in Malaria Parasites" @default.
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- W2914301819 doi "https://doi.org/10.1016/j.pt.2019.01.010" @default.
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