Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914302308> ?p ?o ?g. }
- W2914302308 endingPage "896" @default.
- W2914302308 startingPage "896" @default.
- W2914302308 abstract "Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K can be present in various isoforms, distinguishable by two main structures, namely, phylloquinone (K1) and menaquinones (K2). The difference in structure between K1 and K2 is seen in different absorption rates, tissue distribution, and bioavailability. Although differing in structure, both act as cofactor for the enzyme gamma-glutamylcarboxylase, encompassing both hepatic and extrahepatic activity. Only carboxylated proteins are active and promote a health profile like hemostasis. Furthermore, vitamin K2 in the form of MK-7 has been shown to be a bioactive compound in regulating osteoporosis, atherosclerosis, cancer and inflammatory diseases without risk of negative side effects or overdosing. This review is the first to highlight differences between isoforms vitamin K1 and K2 by means of source, function, and extrahepatic activity." @default.
- W2914302308 created "2019-02-21" @default.
- W2914302308 creator A5002267000 @default.
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- W2914302308 creator A5054724162 @default.
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- W2914302308 creator A5070811893 @default.
- W2914302308 creator A5082162747 @default.
- W2914302308 creator A5013987449 @default.
- W2914302308 creator A5036913002 @default.
- W2914302308 date "2019-02-19" @default.
- W2914302308 modified "2023-10-05" @default.
- W2914302308 title "Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease" @default.
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