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- W2914327833 abstract "Previous studies examining the relationship between asthma, osteoporosis, and pathological fractures found conflicting results. We sought to determine whether asthma is associated with osteoporosis and fractures in US adults. We analyzed data for 198,102,435 children and adults, including 10,127,807 with asthma from the 2006–2012 National Emergency Department Sample, including a 20% cross-sectional sample of emergency care visits throughout the US. In pooled analysis across all 7 years, patients with asthma had significantly higher odds of osteopenia (multivariable logistic regression; adjusted odds ratio [95% confidence intervals]: 1.454 [1.406-1.504]), osteoporosis (1.849 [1.817-1.881]), osteomalacia (1.997 [1.605-2.485]), ankylosing spondylitis (1.487 [1.377-1.606]), and pathological fractures (1.238 [1.204-1.273]). Similarly, asthma was associated with higher odds of osteoporosis (P<0.0001 for all), osteopenia (P<0.0001 for all) and ankylosing spondylitis (P≤0.02 for all) in all 7 years, and osteomalacia in 6 of 7 years (P<0.02 for 2007-2012). There was significant sex- and age-related differences of the associations of asthma with these comorbidities. Asthma was associated with osteopenia, osteoporosis, osteomalacia, ankylosing spondylitis and pathologic fractures." @default.
- W2914327833 created "2019-02-21" @default.
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- W2914327833 date "2019-02-01" @default.
- W2914327833 modified "2023-09-25" @default.
- W2914327833 title "Association of asthma with osteopenia, osteoporosis, osteomalacia and pathological fractures United States adults" @default.
- W2914327833 doi "https://doi.org/10.1016/j.jaci.2018.12.673" @default.
- W2914327833 hasPublicationYear "2019" @default.
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