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- W2914334146 abstract "Alopecia areata is a common, chronic, relapsing and remitting autoimmune disease that produces significant morbidity. Treatment options are limited, have potential toxicity, and are not universally successful. Disease progression is unpredictable; fortunately, many people only ever have mild disease. While genetic factors have been identified, monozygotic twin concordance is only 50%, indicating the presence of environmental cofactors; however, the environmental triggers remain obscure. Spontaneous remission is well recognized and, while welcome, confounds evaluation of valuable therapeutic interventions and has led to a myriad of unconventional remedies and irreproducible results. Despite extensive research into the biology of alopecia areata, no significant new treatment has emerged for this condition in the past 30 years. Commonly used treatments evolved prior to the era of evidence-based medicine, and clinical trial data are limited. Evaluation of the currently available medical interventions and the evidence that supports their use will assist in the management of patients with alopecia areata and its variants alopecia totalis and universalis." @default.
- W2914334146 created "2019-02-21" @default.
- W2914334146 creator A5035044854 @default.
- W2914334146 date "2014-06-06" @default.
- W2914334146 modified "2023-10-17" @default.
- W2914334146 title "Alopecia areata" @default.
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