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- W2914370929 endingPage "132" @default.
- W2914370929 startingPage "120" @default.
- W2914370929 abstract "Neoadjuvant systemic therapy is becoming more commonly used in patients with earlier stages of breast cancer. To assess tumour response to neoadjuvant chemotherapy, pathological evaluation is the gold standard. Depending on the treatment response, the pathological examination of these specimens can be quite challenging. However, a uniform approach to evaluate post-neoadjuvant-treated breast specimens has been lacking. Furthermore, there is no single universally accepted or endorsed classification system for assessing treatment response in this setting. Recent initiatives have attempted to create a standardised protocol for evaluation of post-neoadjuvant breast specimens. This review outlines the necessary information that should be collected prior to macroscopic examination of these specimens, the recommended and most pragmatic approach to tissue sampling for microscopic examination, describes the macroscopic and microscopic features of post-therapy breast specimens, summarises two commonly used systems for classifying treatment response and outlines the critical variables that should be included in the final pathology report." @default.
- W2914370929 created "2019-02-21" @default.
- W2914370929 creator A5011083234 @default.
- W2914370929 creator A5040964442 @default.
- W2914370929 creator A5043473607 @default.
- W2914370929 creator A5055879152 @default.
- W2914370929 creator A5059706622 @default.
- W2914370929 date "2019-01-22" @default.
- W2914370929 modified "2023-10-16" @default.
- W2914370929 title "Breast specimen handling and reporting in the post-neoadjuvant setting: challenges and advances" @default.
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