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• W2914388638 startingPage "2512" @default.
• W2914388638 abstract "An approach for the synthesis of a variety of new β-aryl-β-amino acids has been developed via a palladium-catalyzed auxiliary-directed regioselective Csp3-H arylation of the unactivated β-methylene bond of β-alanine. The use of 8-aminoquinoline amide as an auxiliary efficiently directs the desired regioselective β-Csp3-H functionalization. The developed protocol enables the easy and straightforward access to several high-value β-aryl-β-amino acids useful for peptide engineering, starting from inexpensive and readily available β-alanine precursors in moderate to excellent yields." @default.
• W2914388638 created "2019-02-21" @default.
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• W2914388638 date "2019-02-04" @default.
• W2914388638 modified "2023-10-01" @default.
• W2914388638 title "Regioselective β-Csp³-Arylation of β-Alanine: An Approach for the Exclusive Synthesis of Diverse β-Aryl-β-amino Acids" @default.
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• W2914388638 doi "https://doi.org/10.1021/acs.joc.8b02887" @default.
• W2914388638 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30714366" @default.
• W2914388638 hasPublicationYear "2019" @default.
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