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- W2914391811 abstract "Opioids serve a vital role in the current analgesic array of treatment options. They are useful in acute instances involving severe pain associated with trauma, surgery, and terminal diseases such as cancer. In the past three decades, multiple receptor isoforms and conformations have been reported throughout literature. Most of these studies conducted systemic analyses of opioid receptor function, often generalizing findings from receptor systems in central nervous tissue or exogenously expressing immortalized cell lines as common mechanisms throughout physiology. However, a culmination of innovative experimental data indicates that opioid receptor systems are differentially modulated depending on their anatomic expression profile. Importantly, opioid receptors expressed in the peripheral nervous system undergo regulation uncommon to similar receptors expressed in central nervous system tissues. This distinctive characteristic begs one to question whether peripheral opioid receptors maintain anatomically unique roles, and whether they may serve an analgesic advantage in providing pain relief without promoting addiction." @default.
- W2914391811 created "2019-02-21" @default.
- W2914391811 creator A5042090795 @default.
- W2914391811 date "2019-02-05" @default.
- W2914391811 modified "2023-09-27" @default.
- W2914391811 title "Dynamic Opioid Receptor Regulation in the Periphery" @default.
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- W2914391811 cites W1567081863 @default.
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- W2914391811 cites W1918796765 @default.
- W2914391811 cites W1925074995 @default.
- W2914391811 cites W1927349692 @default.
- W2914391811 cites W1976412816 @default.
- W2914391811 cites W1986172894 @default.
- W2914391811 cites W1988115596 @default.
- W2914391811 cites W2004120139 @default.
- W2914391811 cites W2006523798 @default.
- W2914391811 cites W2007999106 @default.
- W2914391811 cites W2015087988 @default.
- W2914391811 cites W2017096331 @default.
- W2914391811 cites W2018543284 @default.
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- W2914391811 cites W2025046733 @default.
- W2914391811 cites W2026986930 @default.
- W2914391811 cites W2028450129 @default.
- W2914391811 cites W2031782072 @default.
- W2914391811 cites W2033232160 @default.
- W2914391811 cites W2033611080 @default.
- W2914391811 cites W2035258174 @default.
- W2914391811 cites W2043287085 @default.
- W2914391811 cites W2043542724 @default.
- W2914391811 cites W2051974544 @default.
- W2914391811 cites W2052028692 @default.
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- W2914391811 doi "https://doi.org/10.1124/mol.118.114637" @default.
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