FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914405294> ?p ?o ?g. }

• W2914405294 endingPage "602" @default.
• W2914405294 startingPage "602" @default.
• W2914405294 abstract "Unnatural nucleosides possessing unique spectroscopic properties that mimic natural nucleobases in both size and chemical structure are ideally suited for spectroscopic measurements of DNA/RNA structure and dynamics in a site-specific manner. However, such unnatural nucleosides are scarce, which prompts us to explore the utility of a recently found unnatural nucleoside, 4-cyanoindole-2′-deoxyribonucleoside (4CNI-NS), as a site-specific spectroscopic probe of DNA. A recent study revealed that 4CNI-NS is a universal nucleobase that maintains the high fluorescence quantum yield of 4-cyanoindole and that among the four natural nucleobases, only guanine can significantly quench its fluorescence. Herein, we further show that the C≡N stretching frequency of 4CNI-NS is sensitive to the local environment, making it a useful site-specific infrared probe of oligonucleotides. In addition, we demonstrate that the fluorescence-quencher pair formed by 4CNI-NS and guanine can be used to quantitatively assess the binding affinity of a single-stranded DNA to the protein system of interest via fluorescence spectroscopy, among other applications. We believe that this fluorescence binding assay is especially useful as its potentiality allows high-throughput screening of DNA–protein interactions." @default.
• W2914405294 created "2019-02-21" @default.
• W2914405294 creator A5006621344 @default.
• W2914405294 creator A5015225004 @default.
• W2914405294 creator A5015329154 @default.
• W2914405294 creator A5021623971 @default.
• W2914405294 creator A5024525369 @default.
• W2914405294 creator A5068822076 @default.
• W2914405294 creator A5089853082 @default.
• W2914405294 date "2019-02-08" @default.
• W2914405294 modified "2023-10-16" @default.
• W2914405294 title "4-Cyanoindole-2′-deoxyribonucleoside as a Dual&#x0D; Fluorescence and Infrared Probe of DNA Structure&#x0D; and Dynamics" @default.
• W2914405294 cites W1079180211 @default.
• W2914405294 cites W1518071694 @default.
• W2914405294 cites W1732094828 @default.
• W2914405294 cites W1801362421 @default.
• W2914405294 cites W1965093499 @default.
• W2914405294 cites W1966288583 @default.
• W2914405294 cites W1969733268 @default.
• W2914405294 cites W1994448876 @default.
• W2914405294 cites W2021347692 @default.
• W2914405294 cites W2024083021 @default.
• W2914405294 cites W2037017264 @default.
• W2914405294 cites W2044220140 @default.
• W2914405294 cites W2051324340 @default.
• W2914405294 cites W2054618173 @default.
• W2914405294 cites W2057003691 @default.
• W2914405294 cites W2068522177 @default.
• W2914405294 cites W2071558544 @default.
• W2914405294 cites W2078872586 @default.
• W2914405294 cites W2088253659 @default.
• W2914405294 cites W2089951492 @default.
• W2914405294 cites W2095312452 @default.
• W2914405294 cites W2104587229 @default.
• W2914405294 cites W2146361928 @default.
• W2914405294 cites W2169411269 @default.
• W2914405294 cites W2400106899 @default.
• W2914405294 cites W2479196115 @default.
• W2914405294 cites W2571408627 @default.
• W2914405294 cites W2574193311 @default.
• W2914405294 cites W2599122797 @default.
• W2914405294 cites W2620137284 @default.
• W2914405294 cites W2737918677 @default.
• W2914405294 cites W2809849444 @default.
• W2914405294 cites W2848031461 @default.
• W2914405294 cites W4211146992 @default.
• W2914405294 cites W4250548700 @default.
• W2914405294 doi "https://doi.org/10.3390/molecules24030602" @default.
• W2914405294 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6384856" @default.
• W2914405294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30744004" @default.
• W2914405294 hasPublicationYear "2019" @default.
• W2914405294 type Work @default.
• W2914405294 sameAs 2914405294 @default.
• W2914405294 citedByCount "6" @default.
• W2914405294 countsByYear W29144052942019 @default.
• W2914405294 countsByYear W29144052942020 @default.
• W2914405294 countsByYear W29144052942021 @default.
• W2914405294 countsByYear W29144052942022 @default.
• W2914405294 countsByYear W29144052942023 @default.
• W2914405294 crossrefType "journal-article" @default.
• W2914405294 hasAuthorship W2914405294A5006621344 @default.
• W2914405294 hasAuthorship W2914405294A5015225004 @default.
• W2914405294 hasAuthorship W2914405294A5015329154 @default.
• W2914405294 hasAuthorship W2914405294A5021623971 @default.
• W2914405294 hasAuthorship W2914405294A5024525369 @default.
• W2914405294 hasAuthorship W2914405294A5068822076 @default.
• W2914405294 hasAuthorship W2914405294A5089853082 @default.
• W2914405294 hasBestOaLocation W29144052941 @default.
• W2914405294 hasConcept C104317684 @default.
• W2914405294 hasConcept C121332964 @default.
• W2914405294 hasConcept C12554922 @default.
• W2914405294 hasConcept C129312508 @default.
• W2914405294 hasConcept C185592680 @default.
• W2914405294 hasConcept C2776123222 @default.
• W2914405294 hasConcept C2776543447 @default.
• W2914405294 hasConcept C2778301229 @default.
• W2914405294 hasConcept C512185932 @default.
• W2914405294 hasConcept C552990157 @default.
• W2914405294 hasConcept C55493867 @default.
• W2914405294 hasConcept C61234307 @default.
• W2914405294 hasConcept C62520636 @default.
• W2914405294 hasConcept C71240020 @default.
• W2914405294 hasConcept C86803240 @default.
• W2914405294 hasConcept C91881484 @default.
• W2914405294 hasConceptScore W2914405294C104317684 @default.
• W2914405294 hasConceptScore W2914405294C121332964 @default.
• W2914405294 hasConceptScore W2914405294C12554922 @default.
• W2914405294 hasConceptScore W2914405294C129312508 @default.
• W2914405294 hasConceptScore W2914405294C185592680 @default.
• W2914405294 hasConceptScore W2914405294C2776123222 @default.
• W2914405294 hasConceptScore W2914405294C2776543447 @default.
• W2914405294 hasConceptScore W2914405294C2778301229 @default.
• W2914405294 hasConceptScore W2914405294C512185932 @default.
• W2914405294 hasConceptScore W2914405294C552990157 @default.
• W2914405294 hasConceptScore W2914405294C55493867 @default.
• W2914405294 hasConceptScore W2914405294C61234307 @default.
• W2914405294 hasConceptScore W2914405294C62520636 @default.
• W2914405294 hasConceptScore W2914405294C71240020 @default.

• next