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• W2914428606 abstract "Exogenous melatonin can be used to treat sleep disturbance in adults, children, and adolescents. While its short-term use is considered safe, there are some concerns that long-term use might delay children's sexual maturation, possibly by disrupting the decline in nocturnal melatonin levels that occur at the onset of puberty. This narrative review aimed to summarize some of the current knowledge about the potential effects of exogenous melatonin on puberty. We found no clinical studies that experimentally tested the effects of melatonin on pubertal timing in children, but we reviewed the small number of observational studies. We also drew on animal data to try to answer our question. The photoperiod and melatonin-mediated seasonal transitions in sexual activity and breeding in some mammals across the seasons have been used as a model of sexual development in mammals, including humans. The switch from non-sexual activity (in the non-breeding period) to sexual activity (in the breeding period) has been likened to the onset of puberty as there are similarities between the two. We conclude that to investigate an association between melatonin and pubertal timing, it will be important to conduct long-term randomized controlled trials of latency age children and also examine the cellular and systems-level interactions between melatonin and kisspeptin, a recently identified neuropeptide with a locus of action at the gonadotropin releasing hormone neurons that is important in contributing to the timing of puberty onset." @default.
• W2914428606 created "2019-02-21" @default.
• W2914428606 creator A5000176088 @default.
• W2914428606 creator A5015292854 @default.
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• W2914428606 creator A5078360660 @default.
• W2914428606 creator A5086438086 @default.
• W2914428606 date "2019-01-01" @default.
• W2914428606 modified "2023-10-01" @default.
• W2914428606 title "<p>Could long-term administration of melatonin to prepubertal children affect timing of puberty? A clinician&rsquo;s perspective</p>" @default.
• W2914428606 cites W11825656 @default.
• W2914428606 cites W1548249032 @default.
• W2914428606 cites W1549140675 @default.
• W2914428606 cites W1684861691 @default.
• W2914428606 cites W1786658768 @default.
• W2914428606 cites W1808619209 @default.
• W2914428606 cites W1899777542 @default.
• W2914428606 cites W190033692 @default.
• W2914428606 cites W1933059014 @default.
• W2914428606 cites W1966336818 @default.
• W2914428606 cites W1967329472 @default.
• W2914428606 cites W1970978037 @default.
• W2914428606 cites W1976517922 @default.
• W2914428606 cites W1977934055 @default.
• W2914428606 cites W1980507417 @default.
• W2914428606 cites W1984561810 @default.
• W2914428606 cites W1984817673 @default.
• W2914428606 cites W1989078927 @default.
• W2914428606 cites W1997484674 @default.
• W2914428606 cites W2011914364 @default.
• W2914428606 cites W2013825250 @default.
• W2914428606 cites W2015319665 @default.
• W2914428606 cites W2018544004 @default.
• W2914428606 cites W2018572173 @default.
• W2914428606 cites W2025342815 @default.
• W2914428606 cites W2028067503 @default.
• W2914428606 cites W2032072152 @default.
• W2914428606 cites W2033039929 @default.
• W2914428606 cites W2035923887 @default.
• W2914428606 cites W2037152955 @default.
• W2914428606 cites W2037393857 @default.
• W2914428606 cites W2039425156 @default.
• W2914428606 cites W2042324625 @default.
• W2914428606 cites W2043826159 @default.
• W2914428606 cites W2044561635 @default.
• W2914428606 cites W2044608749 @default.
• W2914428606 cites W2047703874 @default.
• W2914428606 cites W2048312460 @default.
• W2914428606 cites W2051549912 @default.
• W2914428606 cites W2053534737 @default.
• W2914428606 cites W2054077890 @default.
• W2914428606 cites W2056648928 @default.
• W2914428606 cites W2060296941 @default.
• W2914428606 cites W2063363450 @default.
• W2914428606 cites W2067130406 @default.
• W2914428606 cites W2067975813 @default.
• W2914428606 cites W2073220855 @default.
• W2914428606 cites W2075256377 @default.
• W2914428606 cites W2075982738 @default.
• W2914428606 cites W2076489548 @default.
• W2914428606 cites W2077563872 @default.
• W2914428606 cites W2079086889 @default.
• W2914428606 cites W2084103659 @default.
• W2914428606 cites W2089725966 @default.
• W2914428606 cites W2090496006 @default.
• W2914428606 cites W2091481481 @default.
• W2914428606 cites W2091648102 @default.
• W2914428606 cites W2092053353 @default.
• W2914428606 cites W2094434713 @default.
• W2914428606 cites W2095683201 @default.
• W2914428606 cites W2096942729 @default.
• W2914428606 cites W2102217390 @default.
• W2914428606 cites W2103204018 @default.
• W2914428606 cites W2107812797 @default.
• W2914428606 cites W2111298759 @default.
• W2914428606 cites W2111561559 @default.
• W2914428606 cites W2114144327 @default.
• W2914428606 cites W2122626461 @default.
• W2914428606 cites W2126566117 @default.
• W2914428606 cites W2129551234 @default.
• W2914428606 cites W2136350449 @default.
• W2914428606 cites W2137539003 @default.
• W2914428606 cites W2152258872 @default.
• W2914428606 cites W2153589742 @default.
• W2914428606 cites W2154023429 @default.
• W2914428606 cites W2156297420 @default.
• W2914428606 cites W2158795213 @default.
• W2914428606 cites W2160721561 @default.
• W2914428606 cites W2161155942 @default.
• W2914428606 cites W2165053957 @default.
• W2914428606 cites W2165852079 @default.
• W2914428606 cites W2168681547 @default.
• W2914428606 cites W2171395404 @default.
• W2914428606 cites W2214622785 @default.
• W2914428606 cites W2408827700 @default.
• W2914428606 cites W2410821953 @default.

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