FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914487964> ?p ?o ?g. }

• W2914487964 endingPage "108588" @default.
• W2914487964 startingPage "108588" @default.
• W2914487964 abstract "Acetylshikonin, a naphthoquinone derivative derived from Lithospermum erythrorhizon, has been shown to have various pharmacological activities; however, its effect on diabetes has rarely been reported. We investigated the hypoglycemic effect of acetylshikonin and found that it decreased blood glucose to a greater extent than insulin and improved glucose tolerance in mice. It also increased glucose uptake in L6 myotubes by inducing the expression and translocation of glucose transporter 4 via decomposition of phosphatidylinositol, increased generation of diacylglycerol, and activation of protein kinase C delta cascades; this is an insulin-, reactive oxygen species-, and AMP-activated protein kinase-independent pathway for glucose uptake. Our findings highlight the antidiabetic potential of acetylshikonin via a possible novel pathway for glucose uptake in L6 myotubes." @default.
• W2914487964 created "2019-02-21" @default.
• W2914487964 creator A5009563185 @default.
• W2914487964 creator A5021833545 @default.
• W2914487964 creator A5045415592 @default.
• W2914487964 creator A5053973352 @default.
• W2914487964 creator A5063206990 @default.
• W2914487964 creator A5071384941 @default.
• W2914487964 date "2019-04-01" @default.
• W2914487964 modified "2023-09-24" @default.
• W2914487964 title "Acetylshikonin stimulates glucose uptake in L6 myotubes via a PLC-β3/PKCδ-dependent pathway" @default.
• W2914487964 cites W1509430244 @default.
• W2914487964 cites W1576671418 @default.
• W2914487964 cites W1884484468 @default.
• W2914487964 cites W1973939264 @default.
• W2914487964 cites W1977371761 @default.
• W2914487964 cites W1980335514 @default.
• W2914487964 cites W199111168 @default.
• W2914487964 cites W1997748823 @default.
• W2914487964 cites W2002202101 @default.
• W2914487964 cites W2004585452 @default.
• W2914487964 cites W2006082012 @default.
• W2914487964 cites W2010763118 @default.
• W2914487964 cites W2017171169 @default.
• W2914487964 cites W2022253164 @default.
• W2914487964 cites W2030137409 @default.
• W2914487964 cites W2036422868 @default.
• W2914487964 cites W2048622566 @default.
• W2914487964 cites W2049587342 @default.
• W2914487964 cites W2064096260 @default.
• W2914487964 cites W2076517751 @default.
• W2914487964 cites W2084374961 @default.
• W2914487964 cites W2086524338 @default.
• W2914487964 cites W2105471728 @default.
• W2914487964 cites W2108106499 @default.
• W2914487964 cites W2110400866 @default.
• W2914487964 cites W2118029488 @default.
• W2914487964 cites W2130859056 @default.
• W2914487964 cites W2135424721 @default.
• W2914487964 cites W2141277427 @default.
• W2914487964 cites W2147669666 @default.
• W2914487964 cites W2167591585 @default.
• W2914487964 cites W2209088499 @default.
• W2914487964 cites W2587119139 @default.
• W2914487964 cites W2784304925 @default.
• W2914487964 doi "https://doi.org/10.1016/j.biopha.2019.01.049" @default.
• W2914487964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30780104" @default.
• W2914487964 hasPublicationYear "2019" @default.
• W2914487964 type Work @default.
• W2914487964 sameAs 2914487964 @default.
• W2914487964 citedByCount "8" @default.
• W2914487964 countsByYear W29144879642020 @default.
• W2914487964 countsByYear W29144879642022 @default.
• W2914487964 countsByYear W29144879642023 @default.
• W2914487964 crossrefType "journal-article" @default.
• W2914487964 hasAuthorship W2914487964A5009563185 @default.
• W2914487964 hasAuthorship W2914487964A5021833545 @default.
• W2914487964 hasAuthorship W2914487964A5045415592 @default.
• W2914487964 hasAuthorship W2914487964A5053973352 @default.
• W2914487964 hasAuthorship W2914487964A5063206990 @default.
• W2914487964 hasAuthorship W2914487964A5071384941 @default.
• W2914487964 hasBestOaLocation W29144879641 @default.
• W2914487964 hasConcept C104317684 @default.
• W2914487964 hasConcept C134018914 @default.
• W2914487964 hasConcept C138626823 @default.
• W2914487964 hasConcept C161573976 @default.
• W2914487964 hasConcept C184235292 @default.
• W2914487964 hasConcept C185592680 @default.
• W2914487964 hasConcept C195794163 @default.
• W2914487964 hasConcept C202751555 @default.
• W2914487964 hasConcept C2777866211 @default.
• W2914487964 hasConcept C2779306644 @default.
• W2914487964 hasConcept C2780610907 @default.
• W2914487964 hasConcept C36020004 @default.
• W2914487964 hasConcept C3763915 @default.
• W2914487964 hasConcept C55493867 @default.
• W2914487964 hasConcept C86803240 @default.
• W2914487964 hasConcept C89200155 @default.
• W2914487964 hasConcept C98274493 @default.
• W2914487964 hasConceptScore W2914487964C104317684 @default.
• W2914487964 hasConceptScore W2914487964C134018914 @default.
• W2914487964 hasConceptScore W2914487964C138626823 @default.
• W2914487964 hasConceptScore W2914487964C161573976 @default.
• W2914487964 hasConceptScore W2914487964C184235292 @default.
• W2914487964 hasConceptScore W2914487964C185592680 @default.
• W2914487964 hasConceptScore W2914487964C195794163 @default.
• W2914487964 hasConceptScore W2914487964C202751555 @default.
• W2914487964 hasConceptScore W2914487964C2777866211 @default.
• W2914487964 hasConceptScore W2914487964C2779306644 @default.
• W2914487964 hasConceptScore W2914487964C2780610907 @default.
• W2914487964 hasConceptScore W2914487964C36020004 @default.
• W2914487964 hasConceptScore W2914487964C3763915 @default.
• W2914487964 hasConceptScore W2914487964C55493867 @default.
• W2914487964 hasConceptScore W2914487964C86803240 @default.
• W2914487964 hasConceptScore W2914487964C89200155 @default.
• W2914487964 hasConceptScore W2914487964C98274493 @default.
• W2914487964 hasLocation W29144879641 @default.
• W2914487964 hasLocation W29144879642 @default.

• next