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• W2914494619 abstract "In this study, polyhydroxybutyrate (PHB) nanoparticles were synthesised following nanoprecipitation method having different solvents and surfactant (Tween 80) concentrations. In this study, PHB nanoparticles were encapsulated with curcumin and subjected for sustained curcumin delivery. Both the curcumin loaded and unloaded PHB nanoparticles were characterised using FTIR, SEM, and AFM. Sizes of the particles were found to be between 60 and 300 nm. The drug encapsulation efficiency and in vitro drug release of the nanoparticles were analysed. Antibacterial activity and anticancer activity were also evaluated. The LC50 values of most of the nanoparticles were found to be between 10 and 20 µg/100 µl, anticancer activity of curcumin loaded PHB nanoparticles were further confirmed by AO/PI staining and mitochondrial depolarisation assay." @default.
• W2914494619 created "2019-02-21" @default.
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• W2914494619 date "2019-04-17" @default.
• W2914494619 modified "2023-10-14" @default.
• W2914494619 title "Surfactant‐mediated synthesis of polyhydroxybutyrate (PHB) nanoparticles for sustained drug delivery" @default.
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• W2914494619 doi "https://doi.org/10.1049/iet-nbt.2018.5053" @default.
• W2914494619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31171747" @default.
• W2914494619 hasPublicationYear "2019" @default.
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