Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914521944> ?p ?o ?g. }
- W2914521944 endingPage "133" @default.
- W2914521944 startingPage "117" @default.
- W2914521944 abstract "Purpose: Triple negative breast cancer is more aggressive than other breast cancer subtypes and accounts for up to 20% of all breast cancers. Despite the poorer prognosis, there are no approved targeted treatments available and chemotherapy remains the only choice. We examined treatment patterns and outcomes among elderly metastatic triple-negative breast cancer (mTNBC) patients in routine clinical practice. Methods: Patients were identified from the linked SEER-Medicare database between 1/1/2001 and 12/31/2013 and included de novo Stage IV (n = 776) and patients with distant metastasis followed an initial diagnosis of Stage I - III disease (n = 1851). Kaplan-Meier analyses and time-varying Cox proportional hazards regression were used to assess overall survival (OS). Results: The mean age at metastatic diagnosis was 77.6 years and 1259 (48%) patients received chemotherapy. Compared to -month longer unadjusted OS compared to the ≥70 cohort (log rank p Conclusions: In this real-world analysis, 48% of elderly mTNBC patients did not receive chemotherapy and a greater proportion were untreated in the ≥70 year old cohort (55%). Although the survival benefits of chemotherapy were greater in the younger cohort, the benefits of treatment persisted in ≥70 year olds. These findings suggest opportunities exist to improve the clinical treatment of elderly mTNBC patients." @default.
- W2914521944 created "2019-02-21" @default.
- W2914521944 creator A5016806055 @default.
- W2914521944 creator A5029025584 @default.
- W2914521944 creator A5043382534 @default.
- W2914521944 creator A5057312624 @default.
- W2914521944 creator A5059832467 @default.
- W2914521944 creator A5079242757 @default.
- W2914521944 date "2019-01-01" @default.
- W2914521944 modified "2023-10-05" @default.
- W2914521944 title "Treatment Patterns and Mortality Risk among Elderly Patients with Metastatic Triple Negative Breast Cancer in the United States: An Observational Cohort Study Using SEER-Medicare Data" @default.
- W2914521944 cites W1759219020 @default.
- W2914521944 cites W1766897822 @default.
- W2914521944 cites W1968437870 @default.
- W2914521944 cites W1976740475 @default.
- W2914521944 cites W1978823332 @default.
- W2914521944 cites W1999684495 @default.
- W2914521944 cites W2000445173 @default.
- W2914521944 cites W2015921398 @default.
- W2914521944 cites W2022684250 @default.
- W2914521944 cites W2076669505 @default.
- W2914521944 cites W2091205535 @default.
- W2914521944 cites W2093577980 @default.
- W2914521944 cites W2094599068 @default.
- W2914521944 cites W2096027508 @default.
- W2914521944 cites W2102118972 @default.
- W2914521944 cites W2108326787 @default.
- W2914521944 cites W2111225997 @default.
- W2914521944 cites W2111714917 @default.
- W2914521944 cites W2120083524 @default.
- W2914521944 cites W2126856198 @default.
- W2914521944 cites W2136655134 @default.
- W2914521944 cites W2150027768 @default.
- W2914521944 cites W2151986118 @default.
- W2914521944 cites W2154433065 @default.
- W2914521944 cites W2158742893 @default.
- W2914521944 cites W2161426850 @default.
- W2914521944 cites W2170602872 @default.
- W2914521944 cites W2290041301 @default.
- W2914521944 cites W2326851875 @default.
- W2914521944 cites W2331849216 @default.
- W2914521944 cites W2340735966 @default.
- W2914521944 cites W2345415641 @default.
- W2914521944 cites W2570618306 @default.
- W2914521944 cites W4248559216 @default.
- W2914521944 cites W4250849363 @default.
- W2914521944 doi "https://doi.org/10.4236/jct.2019.102009" @default.
- W2914521944 hasPublicationYear "2019" @default.
- W2914521944 type Work @default.
- W2914521944 sameAs 2914521944 @default.
- W2914521944 citedByCount "1" @default.
- W2914521944 countsByYear W29145219442021 @default.
- W2914521944 crossrefType "journal-article" @default.
- W2914521944 hasAuthorship W2914521944A5016806055 @default.
- W2914521944 hasAuthorship W2914521944A5029025584 @default.
- W2914521944 hasAuthorship W2914521944A5043382534 @default.
- W2914521944 hasAuthorship W2914521944A5057312624 @default.
- W2914521944 hasAuthorship W2914521944A5059832467 @default.
- W2914521944 hasAuthorship W2914521944A5079242757 @default.
- W2914521944 hasBestOaLocation W29145219441 @default.
- W2914521944 hasConcept C121608353 @default.
- W2914521944 hasConcept C126322002 @default.
- W2914521944 hasConcept C143998085 @default.
- W2914521944 hasConcept C201903717 @default.
- W2914521944 hasConcept C2775930923 @default.
- W2914521944 hasConcept C2776694085 @default.
- W2914521944 hasConcept C2780110267 @default.
- W2914521944 hasConcept C50382708 @default.
- W2914521944 hasConcept C530470458 @default.
- W2914521944 hasConcept C71924100 @default.
- W2914521944 hasConcept C72563966 @default.
- W2914521944 hasConceptScore W2914521944C121608353 @default.
- W2914521944 hasConceptScore W2914521944C126322002 @default.
- W2914521944 hasConceptScore W2914521944C143998085 @default.
- W2914521944 hasConceptScore W2914521944C201903717 @default.
- W2914521944 hasConceptScore W2914521944C2775930923 @default.
- W2914521944 hasConceptScore W2914521944C2776694085 @default.
- W2914521944 hasConceptScore W2914521944C2780110267 @default.
- W2914521944 hasConceptScore W2914521944C50382708 @default.
- W2914521944 hasConceptScore W2914521944C530470458 @default.
- W2914521944 hasConceptScore W2914521944C71924100 @default.
- W2914521944 hasConceptScore W2914521944C72563966 @default.
- W2914521944 hasIssue "02" @default.
- W2914521944 hasLocation W29145219441 @default.
- W2914521944 hasOpenAccess W2914521944 @default.
- W2914521944 hasPrimaryLocation W29145219441 @default.
- W2914521944 hasRelatedWork W2034849620 @default.
- W2914521944 hasRelatedWork W2070780645 @default.
- W2914521944 hasRelatedWork W2092771806 @default.
- W2914521944 hasRelatedWork W2140153507 @default.
- W2914521944 hasRelatedWork W2261491225 @default.
- W2914521944 hasRelatedWork W2317787856 @default.
- W2914521944 hasRelatedWork W2418436192 @default.
- W2914521944 hasRelatedWork W2534174115 @default.
- W2914521944 hasRelatedWork W2705094675 @default.
- W2914521944 hasRelatedWork W2782589310 @default.
- W2914521944 hasVolume "10" @default.
- W2914521944 isParatext "false" @default.