FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914528022> ?p ?o ?g. }

• W2914528022 endingPage "906" @default.
• W2914528022 startingPage "897" @default.
• W2914528022 abstract "The plant-derived biosurfactant aescin is naturally present in many plants and is used for treatment of disorders such as varicose veins and inflammation of veins. The hemolytic activity of this saponin is attributed to its interaction with cholesterol in the red blood cell membrane. This work investigates the phase and aggregation behavior of saponin-containing model membranes consisting of the phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). The aescin concentrations studied range from 1 mol% to 7 mol% with respect to the total lipid content. The methods of choice to elucidate the structural picture are small-angle scattering of X-rays (SAXS) and neutrons (SANS) and cryogenic transmission electron microscopy (cryo-TEM). SANS and SAXS revealed that at lower aescin contents vesicular structures are conserved and vesicles tend to aggregate already at aescin contents of around 1 mol%. Aggregation and vesicle deformation effects are found to be stronger when the phospholipids are in the L [Formula: see text] phase. With increasing aescin content, mixed structures, i.e. aggregated and deformed vesicles and solubilized bilayer fragments, are present. This was proven for a sample with 4 mol% aescin by cryo-TEM. An increasing aescin amount leads to membrane decomposition and free standing bilayers which tend to build stacks at high temperature. These stacks are characterized by SAXS using the modified Caillé theory. Analyses and model dependent fitting reveal formation of well-defined structures beginning at 7 mol% aescin." @default.
• W2914528022 created "2019-02-21" @default.
• W2914528022 creator A5018341144 @default.
• W2914528022 creator A5030543884 @default.
• W2914528022 creator A5042060682 @default.
• W2914528022 creator A5051773366 @default.
• W2914528022 creator A5061581484 @default.
• W2914528022 creator A5065657977 @default.
• W2914528022 creator A5077226368 @default.
• W2914528022 creator A5079203075 @default.
• W2914528022 date "2019-05-01" @default.
• W2914528022 modified "2023-10-17" @default.
• W2914528022 title "Temperature dependent self-organization of DMPC membranes promoted by intermediate amounts of the saponin aescin" @default.
• W2914528022 cites W1967652331 @default.
• W2914528022 cites W1969724933 @default.
• W2914528022 cites W1969791554 @default.
• W2914528022 cites W1976689170 @default.
• W2914528022 cites W1977904100 @default.
• W2914528022 cites W1983676023 @default.
• W2914528022 cites W1984081665 @default.
• W2914528022 cites W1984981562 @default.
• W2914528022 cites W1985310192 @default.
• W2914528022 cites W1986946449 @default.
• W2914528022 cites W1988321785 @default.
• W2914528022 cites W1989675515 @default.
• W2914528022 cites W1999596455 @default.
• W2914528022 cites W2002158695 @default.
• W2914528022 cites W2005514314 @default.
• W2914528022 cites W2009113911 @default.
• W2914528022 cites W2010546419 @default.
• W2914528022 cites W2011799409 @default.
• W2914528022 cites W2015249790 @default.
• W2914528022 cites W2016923434 @default.
• W2914528022 cites W2017230061 @default.
• W2914528022 cites W2029494296 @default.
• W2914528022 cites W2031937350 @default.
• W2914528022 cites W2035149332 @default.
• W2914528022 cites W2049723241 @default.
• W2914528022 cites W2053772994 @default.
• W2914528022 cites W2060164414 @default.
• W2914528022 cites W2060216247 @default.
• W2914528022 cites W2062580204 @default.
• W2914528022 cites W2065051999 @default.
• W2914528022 cites W2069734540 @default.
• W2914528022 cites W2072177283 @default.
• W2914528022 cites W2072397698 @default.
• W2914528022 cites W2072754257 @default.
• W2914528022 cites W2074083797 @default.
• W2914528022 cites W2074223265 @default.
• W2914528022 cites W2075360982 @default.
• W2914528022 cites W2081256532 @default.
• W2914528022 cites W2082400226 @default.
• W2914528022 cites W2082941985 @default.
• W2914528022 cites W2083565871 @default.
• W2914528022 cites W2083683885 @default.
• W2914528022 cites W2084325913 @default.
• W2914528022 cites W2086475835 @default.
• W2914528022 cites W2090150822 @default.
• W2914528022 cites W2103058354 @default.
• W2914528022 cites W2115162513 @default.
• W2914528022 cites W2116676509 @default.
• W2914528022 cites W2121465217 @default.
• W2914528022 cites W2122676372 @default.
• W2914528022 cites W2127463784 @default.
• W2914528022 cites W2129362189 @default.
• W2914528022 cites W2130504343 @default.
• W2914528022 cites W2131184144 @default.
• W2914528022 cites W2155736308 @default.
• W2914528022 cites W2160679445 @default.
• W2914528022 cites W2172101006 @default.
• W2914528022 cites W2345193083 @default.
• W2914528022 cites W2763503028 @default.
• W2914528022 cites W2788367244 @default.
• W2914528022 cites W2887526876 @default.
• W2914528022 cites W3102549908 @default.
• W2914528022 cites W4230342171 @default.
• W2914528022 doi "https://doi.org/10.1016/j.bbamem.2019.01.015" @default.
• W2914528022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30735626" @default.
• W2914528022 hasPublicationYear "2019" @default.
• W2914528022 type Work @default.
• W2914528022 sameAs 2914528022 @default.
• W2914528022 citedByCount "24" @default.
• W2914528022 countsByYear W29145280222018 @default.
• W2914528022 countsByYear W29145280222019 @default.
• W2914528022 countsByYear W29145280222020 @default.
• W2914528022 countsByYear W29145280222021 @default.
• W2914528022 countsByYear W29145280222022 @default.
• W2914528022 countsByYear W29145280222023 @default.
• W2914528022 crossrefType "journal-article" @default.
• W2914528022 hasAuthorship W2914528022A5018341144 @default.
• W2914528022 hasAuthorship W2914528022A5030543884 @default.
• W2914528022 hasAuthorship W2914528022A5042060682 @default.
• W2914528022 hasAuthorship W2914528022A5051773366 @default.
• W2914528022 hasAuthorship W2914528022A5061581484 @default.
• W2914528022 hasAuthorship W2914528022A5065657977 @default.
• W2914528022 hasAuthorship W2914528022A5077226368 @default.
• W2914528022 hasAuthorship W2914528022A5079203075 @default.
• W2914528022 hasBestOaLocation W29145280221 @default.

• next