Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914543341> ?p ?o ?g. }
- W2914543341 endingPage "492" @default.
- W2914543341 startingPage "484" @default.
- W2914543341 abstract "Purpose of review The current review develops the clinical presentations of nonparaneoplastic autoimmune cerebellar ataxia (ACA) and analyzes the association with autoantibodies. Recent findings Emerging evidence suggests that autoimmunity is involved in a significant proportion of sporadic ataxia cases. Moreover, numerous autoantibodies have recently been described in association with sporadic cerebellar ataxia, improving diagnosis and patient categorization. Summary Nonparaneoplastic ACA encompasses postinfectious acute cerebellar ataxia, opsoclonus-myoclonus-ataxia syndrome, and pure cerebellar ataxia with or without autoantibodies. There is still confusion about how to diagnose and classify the patients, and retrospective data suggest that these very rare entities are in fact largely underrecognized. Numerous autoantibodies have been found associated with sporadic ataxia, improving diagnosis accuracy, and patient categorization. However, although anti-glutamate decarboxylase isotype 65 (GAD65), anti-contactin-associated protein 2 (CASPR2), and anti metabotropic glutamate receptor (mGluR1) antibodies are well recognized biomarkers, many other autoantibodies have been described in very small numbers of patients and their specificity is unknown. Efficient biomarkers for ACA are still lacking and in many cases the diagnosis has to rely on a body of converging evidence." @default.
- W2914543341 created "2019-02-21" @default.
- W2914543341 creator A5061141183 @default.
- W2914543341 creator A5081340987 @default.
- W2914543341 date "2019-06-01" @default.
- W2914543341 modified "2023-10-02" @default.
- W2914543341 title "Nonparaneoplastic autoimmune cerebellar ataxias" @default.
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