FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914601885> ?p ?o ?g. }

• W2914601885 endingPage "227" @default.
• W2914601885 startingPage "221" @default.
• W2914601885 abstract "Introduction: One of the major challenges in cancer treatment is the lack of specific and accurate treatment incancer. Data analysis can help to understand the underlying molecular mechanism that leads to better treatment.Increasing availability and reliability of DNA microarray data leads to increase the use of these data in a variety ofcancers. This study aimed at applying and evaluating microarray data analyzing, identification of important pathwaysand gene network for medulloblastoma patients to improve treatment approaches especially target therapy. Methods:In the current study, Microarray gene expression data (GSE50161) were extracted from Geo datasets and then analyzedby the affylmGUI package to predict and investigate upregulated and downregulated genes in medulloblastoma. Then,the important pathways were determined by using software and gene enrichment analyses. Pathways visualizationand network analyses were performed by Cytoscape. Results: A total number of 249 differentially expressed genes(DEGs) were identified in medulloblastoma compared to normal samples. Cell cycle, p53, and FoxO signaling pathwayswere indicated in medulloblastoma, and CDK1, CCNB1, CDK2, and WEE1 were identified as some of the importantgenes in the medulloblastoma. Conclusion: Identification of critical and specific pathway in any disease, in our casemedulloblastoma, can lead us to better clinical management and accurate treatment and target therapy." @default.
• W2914601885 created "2019-02-21" @default.
• W2914601885 creator A5012747365 @default.
• W2914601885 creator A5016342068 @default.
• W2914601885 creator A5026836051 @default.
• W2914601885 creator A5031910916 @default.
• W2914601885 creator A5041792140 @default.
• W2914601885 creator A5051570095 @default.
• W2914601885 creator A5072921540 @default.
• W2914601885 creator A5076550814 @default.
• W2914601885 creator A5078340290 @default.
• W2914601885 date "2019-01-01" @default.
• W2914601885 modified "2023-10-14" @default.
• W2914601885 title "Bioinformatics Analysis of Key Genes and Pathways for Medulloblastoma as a Therapeutic Target" @default.
• W2914601885 cites W1053045602 @default.
• W2914601885 cites W1270834676 @default.
• W2914601885 cites W1557089012 @default.
• W2914601885 cites W1797058518 @default.
• W2914601885 cites W1818592759 @default.
• W2914601885 cites W1964202387 @default.
• W2914601885 cites W1985052767 @default.
• W2914601885 cites W1988228415 @default.
• W2914601885 cites W2012280706 @default.
• W2914601885 cites W2016899610 @default.
• W2914601885 cites W2039379153 @default.
• W2914601885 cites W2042422934 @default.
• W2914601885 cites W2049963771 @default.
• W2914601885 cites W2074270121 @default.
• W2914601885 cites W2080664438 @default.
• W2914601885 cites W2082218127 @default.
• W2914601885 cites W2084170466 @default.
• W2914601885 cites W2090055464 @default.
• W2914601885 cites W2090669153 @default.
• W2914601885 cites W2096293110 @default.
• W2914601885 cites W2111347509 @default.
• W2914601885 cites W2111595180 @default.
• W2914601885 cites W2111842731 @default.
• W2914601885 cites W2118124054 @default.
• W2914601885 cites W2127643721 @default.
• W2914601885 cites W2133465414 @default.
• W2914601885 cites W2137531873 @default.
• W2914601885 cites W2140855509 @default.
• W2914601885 cites W2143381754 @default.
• W2914601885 cites W2144196995 @default.
• W2914601885 cites W2144312231 @default.
• W2914601885 cites W2153583721 @default.
• W2914601885 cites W2155809614 @default.
• W2914601885 cites W2158217645 @default.
• W2914601885 cites W2159675211 @default.
• W2914601885 cites W2170174897 @default.
• W2914601885 cites W2171030481 @default.
• W2914601885 cites W2171473481 @default.
• W2914601885 cites W2332500278 @default.
• W2914601885 cites W2504980652 @default.
• W2914601885 cites W2537623931 @default.
• W2914601885 cites W2717429551 @default.
• W2914601885 doi "https://doi.org/10.31557/apjcp.2019.20.1.221" @default.
• W2914601885 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6485566" @default.
• W2914601885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30678435" @default.
• W2914601885 hasPublicationYear "2019" @default.
• W2914601885 type Work @default.
• W2914601885 sameAs 2914601885 @default.
• W2914601885 citedByCount "4" @default.
• W2914601885 countsByYear W29146018852019 @default.
• W2914601885 countsByYear W29146018852020 @default.
• W2914601885 countsByYear W29146018852023 @default.
• W2914601885 crossrefType "journal-article" @default.
• W2914601885 hasAuthorship W2914601885A5012747365 @default.
• W2914601885 hasAuthorship W2914601885A5016342068 @default.
• W2914601885 hasAuthorship W2914601885A5026836051 @default.
• W2914601885 hasAuthorship W2914601885A5031910916 @default.
• W2914601885 hasAuthorship W2914601885A5041792140 @default.
• W2914601885 hasAuthorship W2914601885A5051570095 @default.
• W2914601885 hasAuthorship W2914601885A5072921540 @default.
• W2914601885 hasAuthorship W2914601885A5076550814 @default.
• W2914601885 hasAuthorship W2914601885A5078340290 @default.
• W2914601885 hasBestOaLocation W29146018851 @default.
• W2914601885 hasConcept C104317684 @default.
• W2914601885 hasConcept C116834253 @default.
• W2914601885 hasConcept C120504264 @default.
• W2914601885 hasConcept C150194340 @default.
• W2914601885 hasConcept C186836561 @default.
• W2914601885 hasConcept C2780789225 @default.
• W2914601885 hasConcept C2781252693 @default.
• W2914601885 hasConcept C29537977 @default.
• W2914601885 hasConcept C502942594 @default.
• W2914601885 hasConcept C54355233 @default.
• W2914601885 hasConcept C59822182 @default.
• W2914601885 hasConcept C60644358 @default.
• W2914601885 hasConcept C70721500 @default.
• W2914601885 hasConcept C8415881 @default.
• W2914601885 hasConcept C86803240 @default.
• W2914601885 hasConcept C95371953 @default.
• W2914601885 hasConceptScore W2914601885C104317684 @default.
• W2914601885 hasConceptScore W2914601885C116834253 @default.
• W2914601885 hasConceptScore W2914601885C120504264 @default.
• W2914601885 hasConceptScore W2914601885C150194340 @default.
• W2914601885 hasConceptScore W2914601885C186836561 @default.

• next