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- W2914622025 abstract "A 43-year-old man, troubleshooting a photocoating and developing machine within a clean room dealing with chemicals, was found unresponsive lying face down on the floor with severe burns over the chest and left upper limb. The worker was resuscitated and thorough decontamination was done, but he continued to deteriorate and passed away. Post-mortem toxicology testing yielded negative results. It was later established that one of the chemicals in the clean room was tetramethylammonium hydroxide. Tetramethylammonium hydroxide is a substance commonly used in the semiconductor and photoelectric industries, known for its corrosive effects of the alkaline hydroxyl group but its lethal ganglionic blocking effect on skin exposure is often forgotten as very few deaths associated with its use have been reported. As far as we know, there is no known method of analytical toxicological testing of tetramethylammonium hydroxide in biological specimens. The few reported cases of death were concluded purely based on the circumstances. However, police recovered a white paper napkin found around the deceased. It was detected to have tetramethylammonium ion. Correlating the circumstances and the toxicology finding on the napkin, the cause of death was deemed to be consistent with tetramethylammonium hydroxide toxicity." @default.
- W2914622025 created "2019-02-21" @default.
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- W2914622025 date "2019-02-01" @default.
- W2914622025 modified "2023-09-25" @default.
- W2914622025 title "Mystery solved by a napkin: a fatal case of tetramethylammonium hydroxide poisoning" @default.
- W2914622025 doi "https://doi.org/10.1016/j.pathol.2018.12.328" @default.
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