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- W2914646002 abstract "Growth traits are mainly determined by genetic factors. SIRT4, a class II sirtuin, predominantly acts as an ADP-ribosyltransferase and inhibits fatty acid oxidation. In this study, a total of 1005 cattle belonging to five indigenous Chinese breeds were used to evaluate the relationship between the potential insertions/deletions (indels) within the SIRT4 gene and growth traits. The results revealed that only one intronic variation was present, which showed Hardy-Weinberg equilibrium (p > 0.05) in all the populations. The relationship analyses indicated that this indel was significantly associated with growth traits (p < 0.05), implying that SIRT4 significantly affects the growth traits. Therefore, the deletion mutation within the SIRT4 gene could be considered as a molecular marker to screen for growth traits in the cattle industry." @default.
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- W2914646002 date "2019-01-28" @default.
- W2914646002 modified "2023-09-23" @default.
- W2914646002 title "Relationship between an indel mutation within the <i>SIRT4</i> gene and growth traits in Chinese cattle" @default.
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- W2914646002 doi "https://doi.org/10.1080/10495398.2018.1520716" @default.
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