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• W2914681454 endingPage "569" @default.
• W2914681454 startingPage "552" @default.
• W2914681454 abstract "Sleep macrostructure is commonly disturbed after surgery. Postoperative pain control remains challenging. Given the bidirectional interaction between sleep and pain, understanding the role of modulation of sleep during the perioperative period on postoperative pain is needed.This was a systematic review. Controlled trials examining the effects of perioperative sleep-promoting pharmacological agents on postoperative pain and analgesic consumption were identified through a systematic search strategy utilizing multiple electronic databases.Fourteen studies (9 melatonin, 5 zolpidem) involving 921 patients (melatonin n = 586, zolpidem n = 335) were included. Compared to placebo, melatonin reduced postoperative pain scores by ≥30% and significantly decreased opioid consumption in 3 studies (postoperative day [POD] 1-2), whereas 4 studies reported no significant effect of melatonin on postoperative pain. Compared to placebo, zolpidem reduced postoperative pain scores during POD1-7/POD1-14 in 2 studies, but only 1 trial suggested clinically meaningful improvement (ie, relative reduction of pain score ≥ 30%). Whereas 3 zolpidem trials showed no significant differences regarding postoperative pain ratings, zolpidem treatment was associated with decreased analgesic consumption in 4 out of 5 trials. Several limitations of the included studies were identified; only 1 study out of 14 was deemed to be at low risk of bias, and heterogeneity of the study design and outcome assessment precluded meta-analysis.Perioperative addition of a sleep-promoting pharmacological agent may improve pain control, but underlying evidence is weak and results are inconsistent. Only 5 of the 14 studies objectively evaluated changes in sleep (polysomnography, 2 zolpidem studies; actigraphy, 3 melatonin studies), which complicates conclusions regarding links between perioperative sleep and pain." @default.
• W2914681454 created "2019-02-21" @default.
• W2914681454 creator A5003868980 @default.
• W2914681454 creator A5005936736 @default.
• W2914681454 date "2019-03-22" @default.
• W2914681454 modified "2023-10-14" @default.
• W2914681454 title "Perioperative Pharmacological Sleep‐Promotion and Pain Control: A Systematic Review" @default.
• W2914681454 cites W129217036 @default.
• W2914681454 cites W1493696659 @default.
• W2914681454 cites W190565509 @default.
• W2914681454 cites W1922877606 @default.
• W2914681454 cites W1939020017 @default.
• W2914681454 cites W1945898546 @default.
• W2914681454 cites W1963639121 @default.
• W2914681454 cites W1967320240 @default.
• W2914681454 cites W1973190276 @default.
• W2914681454 cites W1981237770 @default.
• W2914681454 cites W1982471329 @default.
• W2914681454 cites W1985990153 @default.
• W2914681454 cites W1988067442 @default.
• W2914681454 cites W1999902541 @default.
• W2914681454 cites W1999924882 @default.
• W2914681454 cites W2002133521 @default.
• W2914681454 cites W2003402040 @default.
• W2914681454 cites W2003577104 @default.
• W2914681454 cites W2003856118 @default.
• W2914681454 cites W2004015751 @default.
• W2914681454 cites W2004938830 @default.
• W2914681454 cites W2005396232 @default.
• W2914681454 cites W2008588675 @default.
• W2914681454 cites W2009185707 @default.
• W2914681454 cites W2017794171 @default.
• W2914681454 cites W2018634655 @default.
• W2914681454 cites W2018714439 @default.
• W2914681454 cites W2020672544 @default.
• W2914681454 cites W2022024201 @default.
• W2914681454 cites W2024160456 @default.
• W2914681454 cites W2033988957 @default.
• W2914681454 cites W2043287573 @default.
• W2914681454 cites W2049188042 @default.
• W2914681454 cites W2052564398 @default.
• W2914681454 cites W2054421884 @default.
• W2914681454 cites W2056795075 @default.
• W2914681454 cites W2058287449 @default.
• W2914681454 cites W2058537083 @default.
• W2914681454 cites W2059300138 @default.
• W2914681454 cites W2061879294 @default.
• W2914681454 cites W2062516703 @default.
• W2914681454 cites W2065506323 @default.
• W2914681454 cites W2068248998 @default.
• W2914681454 cites W2071109470 @default.
• W2914681454 cites W2072369333 @default.
• W2914681454 cites W2074381826 @default.
• W2914681454 cites W2075715972 @default.
• W2914681454 cites W2077109483 @default.
• W2914681454 cites W2079305234 @default.
• W2914681454 cites W2084429447 @default.
• W2914681454 cites W2086969201 @default.
• W2914681454 cites W2088045668 @default.
• W2914681454 cites W2090466892 @default.
• W2914681454 cites W2094472729 @default.
• W2914681454 cites W2094950559 @default.
• W2914681454 cites W2098923148 @default.
• W2914681454 cites W2098995101 @default.
• W2914681454 cites W2101623533 @default.
• W2914681454 cites W2101725333 @default.
• W2914681454 cites W2102228952 @default.
• W2914681454 cites W2105132636 @default.
• W2914681454 cites W2109979737 @default.
• W2914681454 cites W2111311321 @default.
• W2914681454 cites W2116205810 @default.
• W2914681454 cites W2119795186 @default.
• W2914681454 cites W2120012224 @default.
• W2914681454 cites W2120491768 @default.
• W2914681454 cites W2120887129 @default.
• W2914681454 cites W2125158184 @default.
• W2914681454 cites W2126873517 @default.
• W2914681454 cites W2130141996 @default.
• W2914681454 cites W2131704398 @default.
• W2914681454 cites W2136441178 @default.
• W2914681454 cites W2140192918 @default.
• W2914681454 cites W2140732811 @default.
• W2914681454 cites W2150662344 @default.
• W2914681454 cites W2151016127 @default.
• W2914681454 cites W2153953620 @default.
• W2914681454 cites W2158773937 @default.
• W2914681454 cites W2159733957 @default.
• W2914681454 cites W2162334845 @default.
• W2914681454 cites W2167864730 @default.
• W2914681454 cites W2168135789 @default.
• W2914681454 cites W2170601589 @default.
• W2914681454 cites W2172137782 @default.
• W2914681454 cites W2226760253 @default.
• W2914681454 cites W2346095512 @default.
• W2914681454 cites W2346896034 @default.
• W2914681454 cites W2489333009 @default.
• W2914681454 cites W2547806892 @default.
• W2914681454 cites W2586327237 @default.

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