FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914727892> ?p ?o ?g. }

• W2914727892 abstract "Background: Cerebral vasospasm remains a significant cause of morbidity and mortality in patients after aneurysmal subarachnoid hemorrhage (aSAH). Recently, there has been growing interest in the associations between development of vasospasm and inflammatory cytokines, leukocytes, and pro-thrombotic pathways. Thus far, these investigations have been confined to the prediction of vasospasm and delayed cerebral ischemia rather than the prediction of clinical outcome. We aimed to identify various hematologic predictors of clinical outcome in patients diagnosed with cerebral vasospasm following aSAH. Methods: All aSAH patients between 2009-2016 at our institution were reviewed. Patients with symptoms and radiographic evidence of cerebral vasospasm were identified. We assessed baseline and outcome data, including patient demographics, initial aneurysm specifications, management of aSAH and subsequent vasospasm(s), hematologic variables, and 90-day functional outcome (modified Rankin Scale 0-6). Results: One-hundred-ten patients with cerebral vasospasm were identified. Forty-three patients had a mRS score of 3-6 at 90 days following discharge. In multivariate logistic regression analysis, lymphocyte count on day of aSAH (OR=4.82, CI 95% 1.68—13.89), high Hunt-Hess grade (OR=4.23, CI 95% 1.19—15.03), external ventricular drain use (OR=11.18, CI 95% 1.27—98.42), and severe vasospasm (OR=8.25, CI 95% 2.26—30.13) were found to be predictors of poor clinical outcome. Conclusions: Elevated lymphocyte count following aSAH was associated with a significantly higher rate of poor clinical outcome in patients who developed vasospasm. Several studies have focused on various inflammatory markers, but little attention has been paid to lymphocyte count. Closer monitoring with a lower threshold for endovascular treatment may be indicated in this patient population and could improve clinical outcomes." @default.
• W2914727892 created "2019-02-21" @default.
• W2914727892 creator A5018078038 @default.
• W2914727892 creator A5034282536 @default.
• W2914727892 creator A5050891062 @default.
• W2914727892 creator A5066105568 @default.
• W2914727892 date "2019-02-01" @default.
• W2914727892 modified "2023-10-18" @default.
• W2914727892 title "Abstract TP549: Lymphocyte Count Predicts Poor Clinical Outcome in Patients With Vasospasm Following Subarachnoid Hemorrhage" @default.
• W2914727892 doi "https://doi.org/10.1161/str.50.suppl_1.tp549" @default.
• W2914727892 hasPublicationYear "2019" @default.
• W2914727892 type Work @default.
• W2914727892 sameAs 2914727892 @default.
• W2914727892 citedByCount "1" @default.
• W2914727892 countsByYear W29147278922023 @default.
• W2914727892 crossrefType "journal-article" @default.
• W2914727892 hasAuthorship W2914727892A5018078038 @default.
• W2914727892 hasAuthorship W2914727892A5034282536 @default.
• W2914727892 hasAuthorship W2914727892A5050891062 @default.
• W2914727892 hasAuthorship W2914727892A5066105568 @default.
• W2914727892 hasConcept C126322002 @default.
• W2914727892 hasConcept C164705383 @default.
• W2914727892 hasConcept C2776820941 @default.
• W2914727892 hasConcept C2777736543 @default.
• W2914727892 hasConcept C2778506911 @default.
• W2914727892 hasConcept C2780931571 @default.
• W2914727892 hasConcept C3020199598 @default.
• W2914727892 hasConcept C541997718 @default.
• W2914727892 hasConcept C71924100 @default.
• W2914727892 hasConceptScore W2914727892C126322002 @default.
• W2914727892 hasConceptScore W2914727892C164705383 @default.
• W2914727892 hasConceptScore W2914727892C2776820941 @default.
• W2914727892 hasConceptScore W2914727892C2777736543 @default.
• W2914727892 hasConceptScore W2914727892C2778506911 @default.
• W2914727892 hasConceptScore W2914727892C2780931571 @default.
• W2914727892 hasConceptScore W2914727892C3020199598 @default.
• W2914727892 hasConceptScore W2914727892C541997718 @default.
• W2914727892 hasConceptScore W2914727892C71924100 @default.
• W2914727892 hasIssue "Suppl_1" @default.
• W2914727892 hasLocation W29147278921 @default.
• W2914727892 hasOpenAccess W2914727892 @default.
• W2914727892 hasPrimaryLocation W29147278921 @default.
• W2914727892 hasRelatedWork W1515578797 @default.
• W2914727892 hasRelatedWork W2053438199 @default.
• W2914727892 hasRelatedWork W2129034760 @default.
• W2914727892 hasRelatedWork W2413781940 @default.
• W2914727892 hasRelatedWork W2465613368 @default.
• W2914727892 hasRelatedWork W2560940010 @default.
• W2914727892 hasRelatedWork W2955911177 @default.
• W2914727892 hasRelatedWork W2956097462 @default.
• W2914727892 hasRelatedWork W4321793414 @default.
• W2914727892 hasRelatedWork W3032372237 @default.
• W2914727892 hasVolume "50" @default.
• W2914727892 isParatext "false" @default.
• W2914727892 isRetracted "false" @default.
• W2914727892 magId "2914727892" @default.
• W2914727892 workType "article" @default.