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• W2914760194 abstract "Abstract Coding and long non-coding RNA (lncRNA) metabolism is now revealing its crucial role in Amyotrophic Lateral Sclerosis (ALS) pathogenesis. In this work, we present a dataset obtained via Illumina RNA-seq analysis on Peripheral Blood Mononuclear Cells (PBMCs) from sporadic and mutated ALS patients (mutations in FUS , TARDBP , SOD1 and VCP genes) and healthy controls. This dataset allows the whole-transcriptome characterization of PBMCs content, both in terms of coding and non-coding RNAs, in order to compare the disease state to the healthy controls, both for sporadic patients and for mutated patients. Our dataset is a starting point for the omni-comprehensive analysis of coding and lncRNAs, from an easy to withdraw, manage and store tissue that shows to be a suitable model for RNA profiling in ALS." @default.
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• W2914760194 date "2019-02-05" @default.
• W2914760194 modified "2023-10-18" @default.
• W2914760194 title "RNA-Seq profiling in peripheral blood mononuclear cells of amyotrophic lateral sclerosis patients and controls" @default.
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• W2914760194 doi "https://doi.org/10.1038/sdata.2019.6" @default.
• W2914760194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6362931" @default.
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