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- W2914772188 abstract "Cystic fibrosis (CF) was first identified as an important cause of failure to thrive, malabsorption of fat, fat-soluble vitamin deficiency, and severe, recurrent, or persistent lung infection in young infants. The interaction between nutrition and lung function is complex, but at all ages there are challenges to nutritional management. It is the lung disease which is the usual cause of death. Other, less constant but common clinical features of CF which affect the patient's nutritional needs, include liver disease, CF-related diabetes mellitus (CFRD) and osteoporosis. Selenium is an essential component of the antioxidant glutathione peroxidase, which is secreted on to the bronchial and other epithelial surfaces, including the pancreatic duct, like chloride, through the CFTR channel. Nutritional support of young children with pancreatic insufficiency established at birth will continue to be a priority, helped by early diagnosis of CF through neonatal screening, which is now widely practised in relevant countries." @default.
- W2914772188 created "2019-02-21" @default.
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- W2914772188 date "2015-07-24" @default.
- W2914772188 modified "2023-09-24" @default.
- W2914772188 title "Cystic Fibrosis" @default.
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- W2914772188 doi "https://doi.org/10.1002/9781119211945.ch24" @default.
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