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• W2914787994 abstract "Solid organ transplant (SOT) recipients have an approximately 2-fold greater risk of developing and dying from a malignancy compared to the general population. Among the gynecologic cancers, including uterine, cervical, vaginal, vulvar, and ovarian, the HPV-related cancers are known to increase among women posttransplant compared to women in the general population, but less is known about the risk of uterine and ovarian cancers. This review provides an overview of the epidemiology of gynecologic cancers after solid organ transplantation, as well as the pathophysiology, management, and specific risk factors associated with these cancers. Closer surveillance for cervical cancers is warranted and larger studies are needed to assess whether and how uterine and ovarian cancers are associated with excess incidence and mortality. Such studies may lead to improvements in screening, prevention, and treatment before and after transplantation. Solid organ transplant (SOT) recipients have an approximately 2-fold greater risk of developing and dying from a malignancy compared to the general population. Among the gynecologic cancers, including uterine, cervical, vaginal, vulvar, and ovarian, the HPV-related cancers are known to increase among women posttransplant compared to women in the general population, but less is known about the risk of uterine and ovarian cancers. This review provides an overview of the epidemiology of gynecologic cancers after solid organ transplantation, as well as the pathophysiology, management, and specific risk factors associated with these cancers. Closer surveillance for cervical cancers is warranted and larger studies are needed to assess whether and how uterine and ovarian cancers are associated with excess incidence and mortality. Such studies may lead to improvements in screening, prevention, and treatment before and after transplantation." @default.
• W2914787994 created "2019-02-21" @default.
• W2914787994 creator A5062695959 @default.
• W2914787994 creator A5089188044 @default.
• W2914787994 creator A5090963692 @default.
• W2914787994 date "2019-05-01" @default.
• W2914787994 modified "2023-10-14" @default.
• W2914787994 title "Gynecologic cancers and solid organ transplantation" @default.
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• W2914787994 doi "https://doi.org/10.1111/ajt.15292" @default.
• W2914787994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30725527" @default.
• W2914787994 hasPublicationYear "2019" @default.
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