FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914789358> ?p ?o ?g. }

• W2914789358 endingPage "S824" @default.
• W2914789358 startingPage "S824" @default.
• W2914789358 abstract "A 63 year-old Hispanic male with history of hypertension and nephrolithiasis presented for an averagerisk colorectal cancer screening colonoscopy. During the study he was found with a large, raised submucosal lesion in cecum, specifically arising at the appendiceal orifice with a “volcano sign” appearance as seen in mucocele of the appendix (Image 1). Epithelial biopsy of this lesion was taken and reported a serrated adenomatous tissue. An abdominopelvic CT described a distended appendix with intraluminal fluid density. Occluding its orifice, there was a polypoid density measuring 2.0 cm x 2.3 cm x 1.7 cm with Hounsfield units compatible with soft tissue density (Image 2). There was no adjacent lymphadenopathy or focal inflammatory changes. An appendiceal mucocele as well as an obstructing adenocarcinoma were considered in the differential diagnosis. The patient underwent a laparoscopic right hemicolectomy. Pathology report confirmed a vermiform appendix with a sessile serrated adenoma occupying the entire length of the appendix, unremarkable margins of excision and lymph nodes (Image 3). Sessile serrated adenomas are a relatively recent described entity most commonly occurring in the right colon and rarely in the appendix. The term serrated adenomas originate from its histological findings of adenomas with saw tooth-like dysplastic epithelium found in more than 50% of basal crypts. It has been recognized that these lesions portraits microsatellites instability, which is a molecular pathway different from conventional adenomas and a risk factor for colorectal cancer. From 20 to 30% of colorectal cancers arise through the serrated polyp pathway. In the first small case series reported by Rubio in 2004, most serrated and villous adenomas of the appendix were diagnosed as incidental findings during appendectomy and autopsy, and appeared to be highly aggressive lesions in comparison to those arising from the colorectum. Except for rare case reports and a few case series, the true incidence of appendiceal serrated polyps is unknown. This case report describes a sessile serrated adenoma located in the appendix diagnosed by a screening colonoscopy and successfully treated by surgical resection.Figure: Endoscopic findings of a raised submucosal lesion arising at appendiceal orifice.Figure: The appendix is distended by intraluminal fluid density. No periappendiceal inflammatory changes. Occluding its orifice, there is a polypoid density which measures approximate 2 cm transversely x 2.3 cm AP x approximately 1.7 cm vertically. It shows Hounsfield unit measurements compatible with soft tissue density. No adjacent significant lymphadenopathy noted.Figure: The sections of the appendix in H&E stain show serrated mucosa throughout the appendix with irregular crypt branching, dilation and serration of crypt bases. These changes are limited to the mucosa with no invasion into the submucosa." @default.
• W2914789358 created "2019-02-21" @default.
• W2914789358 creator A5025669028 @default.
• W2914789358 creator A5028546631 @default.
• W2914789358 creator A5037292773 @default.
• W2914789358 date "2017-10-01" @default.
• W2914789358 modified "2023-09-26" @default.
• W2914789358 title "Sessile Serrated Adenoma of the Appendix in an Asymptomatic Patient" @default.
• W2914789358 doi "https://doi.org/10.14309/00000434-201710001-01507" @default.
• W2914789358 hasPublicationYear "2017" @default.
• W2914789358 type Work @default.
• W2914789358 sameAs 2914789358 @default.
• W2914789358 citedByCount "0" @default.
• W2914789358 crossrefType "journal-article" @default.
• W2914789358 hasAuthorship W2914789358A5025669028 @default.
• W2914789358 hasAuthorship W2914789358A5028546631 @default.
• W2914789358 hasAuthorship W2914789358A5037292773 @default.
• W2914789358 hasConcept C121608353 @default.
• W2914789358 hasConcept C126322002 @default.
• W2914789358 hasConcept C126838900 @default.
• W2914789358 hasConcept C142724271 @default.
• W2914789358 hasConcept C151730666 @default.
• W2914789358 hasConcept C2776364125 @default.
• W2914789358 hasConcept C2777428134 @default.
• W2914789358 hasConcept C2778435480 @default.
• W2914789358 hasConcept C2778741325 @default.
• W2914789358 hasConcept C526805850 @default.
• W2914789358 hasConcept C71924100 @default.
• W2914789358 hasConcept C86803240 @default.
• W2914789358 hasConceptScore W2914789358C121608353 @default.
• W2914789358 hasConceptScore W2914789358C126322002 @default.
• W2914789358 hasConceptScore W2914789358C126838900 @default.
• W2914789358 hasConceptScore W2914789358C142724271 @default.
• W2914789358 hasConceptScore W2914789358C151730666 @default.
• W2914789358 hasConceptScore W2914789358C2776364125 @default.
• W2914789358 hasConceptScore W2914789358C2777428134 @default.
• W2914789358 hasConceptScore W2914789358C2778435480 @default.
• W2914789358 hasConceptScore W2914789358C2778741325 @default.
• W2914789358 hasConceptScore W2914789358C526805850 @default.
• W2914789358 hasConceptScore W2914789358C71924100 @default.
• W2914789358 hasConceptScore W2914789358C86803240 @default.
• W2914789358 hasLocation W29147893581 @default.
• W2914789358 hasOpenAccess W2914789358 @default.
• W2914789358 hasPrimaryLocation W29147893581 @default.
• W2914789358 hasRelatedWork W11665586 @default.
• W2914789358 hasRelatedWork W1587686864 @default.
• W2914789358 hasRelatedWork W1999984408 @default.
• W2914789358 hasRelatedWork W2273222019 @default.
• W2914789358 hasRelatedWork W2406204692 @default.
• W2914789358 hasRelatedWork W2417774362 @default.
• W2914789358 hasRelatedWork W2944981773 @default.
• W2914789358 hasRelatedWork W2949129511 @default.
• W2914789358 hasRelatedWork W3029016851 @default.
• W2914789358 hasRelatedWork W3031074271 @default.
• W2914789358 hasVolume "112" @default.
• W2914789358 isParatext "false" @default.
• W2914789358 isRetracted "false" @default.
• W2914789358 magId "2914789358" @default.
• W2914789358 workType "article" @default.