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- W2914796388 abstract "Dental implantology allows replacement of failing teeth providing the patient with a general improvement of health. Unfortunately not all reconstructions succeed, as a consequence of the development of infections of bacterial origin on the implant surface. Surface topography is known to modulate a differential response to bacterial and mammalian cells but topographical measurements are often limited to vertical parameters. In this work we have extended the topographical measurements also to lateral and hybrid parameters of the five most representative implant and prosthetic component surfaces and correlated the results with bacterial and mammalian cell adhesion and proliferation outcomes. Primary human oral gingival fibroblast (gum cells) and the bacterial strains: Streptococcus mutans , Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans , implicated in infectious processes in the oral/implant environment were employed in the presence or absence of human saliva. The results confirm that even though not all the measured surface is available for bacteria to adhere, the overall race for the surface between cells and bacteria is more favourable to the smoother surfaces (nitrided, as machined or lightly acid etched) than to the rougher ones (strong acid etched or sandblasted/acid etched)." @default.
- W2914796388 created "2019-02-21" @default.
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- W2914796388 date "2019-02-10" @default.
- W2914796388 modified "2023-10-16" @default.
- W2914796388 title "Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains" @default.
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- W2914796388 doi "https://doi.org/10.1155/2019/8456342" @default.
- W2914796388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6431371" @default.
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