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- W2914798412 abstract "Intrauterine growth restriction (IUGR) remains a major problem in swine production since the associated low birth weight leads to high rates of pre-weaning morbidity and mortality, and permanent retardation of growth and development. The underlying regulatory mechanisms from the aspects of epigenetic modification has received widespread attention. Studies explore the changes in genome wide methylation in small intestine (SI), liver and longissimus dorsi muscle (LDM) between IUGR and normal birth weight (NBW) newborn piglets using a methylated DNA immunoprecipitation-sequencing (MeDIP-Seq) approach. The data demonstrated that methylated peaks were prominently distributed in distal intergenic regions and the quantities of peaks in IUGR piglets were more than that of NBW piglets. IUGR piglets had relatively high methylated level in promoters, introns and coding exons in all the three tissues. Through KEGG pathway analysis of differentially methylated genes found that 33, 54 and 5 differentially methylated genes in small intestine, liver and longissimus dorsi muscle between NBW and IUGR piglets, respectively, which are related to development and differentiation, carbohydrate and energy metabolism, lipid metabolism, protein turnover, immune response, detoxification, oxidative stress and apoptosis pathway. The objective of this review is to assess the impact of differentially methylation status on developmental delay, metabolic disorders and immune deficiency of IUGR piglets." @default.
- W2914798412 created "2019-02-21" @default.
- W2914798412 creator A5003952746 @default.
- W2914798412 creator A5009494606 @default.
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- W2914798412 creator A5061923210 @default.
- W2914798412 creator A5063403085 @default.
- W2914798412 date "2019-06-27" @default.
- W2914798412 modified "2023-10-16" @default.
- W2914798412 title "Intrauterine Growth Restriction Alters the Genome-Wide DNA Methylation Profiles in Small Intestine, Liver and Longissimus Dorsi Muscle of Newborn Piglets" @default.
- W2914798412 cites W108802658 @default.
- W2914798412 cites W1541883444 @default.
- W2914798412 cites W1777393796 @default.
- W2914798412 cites W1897468685 @default.
- W2914798412 cites W1955122085 @default.
- W2914798412 cites W1969883059 @default.
- W2914798412 cites W1975025518 @default.
- W2914798412 cites W1977247288 @default.
- W2914798412 cites W1980482827 @default.
- W2914798412 cites W1982269632 @default.
- W2914798412 cites W1983298212 @default.
- W2914798412 cites W1986975893 @default.
- W2914798412 cites W1988924112 @default.
- W2914798412 cites W1990122324 @default.
- W2914798412 cites W1990594153 @default.
- W2914798412 cites W1992454623 @default.
- W2914798412 cites W1995773697 @default.
- W2914798412 cites W1996666118 @default.
- W2914798412 cites W1999408877 @default.
- W2914798412 cites W2007027806 @default.
- W2914798412 cites W2010513986 @default.
- W2914798412 cites W2011333882 @default.
- W2914798412 cites W2018439302 @default.
- W2914798412 cites W2022042901 @default.
- W2914798412 cites W2022892655 @default.
- W2914798412 cites W2025493596 @default.
- W2914798412 cites W2028403153 @default.
- W2914798412 cites W2035939797 @default.
- W2914798412 cites W2042296250 @default.
- W2914798412 cites W2045552935 @default.
- W2914798412 cites W2056386643 @default.
- W2914798412 cites W2057297290 @default.
- W2914798412 cites W2057396623 @default.
- W2914798412 cites W2059180570 @default.
- W2914798412 cites W2059299661 @default.
- W2914798412 cites W2061549656 @default.
- W2914798412 cites W2063302086 @default.
- W2914798412 cites W2070127502 @default.
- W2914798412 cites W2071898789 @default.
- W2914798412 cites W2074174777 @default.
- W2914798412 cites W2075520416 @default.
- W2914798412 cites W2077307887 @default.
- W2914798412 cites W2081998281 @default.
- W2914798412 cites W2084404692 @default.
- W2914798412 cites W2090204319 @default.
- W2914798412 cites W2090279893 @default.
- W2914798412 cites W2096753107 @default.
- W2914798412 cites W2096783993 @default.
- W2914798412 cites W2098517908 @default.
- W2914798412 cites W2099410699 @default.
- W2914798412 cites W2100649128 @default.
- W2914798412 cites W2102274308 @default.
- W2914798412 cites W2114184154 @default.
- W2914798412 cites W2119731689 @default.
- W2914798412 cites W2120760229 @default.
- W2914798412 cites W2122745596 @default.
- W2914798412 cites W2125491563 @default.
- W2914798412 cites W2131491125 @default.
- W2914798412 cites W2133300386 @default.
- W2914798412 cites W2134239458 @default.
- W2914798412 cites W2134948484 @default.
- W2914798412 cites W2136597063 @default.
- W2914798412 cites W2143205933 @default.
- W2914798412 cites W2144444795 @default.
- W2914798412 cites W2149700046 @default.
- W2914798412 cites W2150125052 @default.
- W2914798412 cites W2150968312 @default.
- W2914798412 cites W2156581836 @default.
- W2914798412 cites W2156624679 @default.
- W2914798412 cites W2158332761 @default.
- W2914798412 cites W2161197995 @default.
- W2914798412 cites W2164947902 @default.
- W2914798412 cites W2173423384 @default.
- W2914798412 cites W2279194939 @default.
- W2914798412 cites W2285561487 @default.
- W2914798412 cites W2311549194 @default.
- W2914798412 cites W2321119744 @default.
- W2914798412 cites W2323015755 @default.
- W2914798412 cites W2327263867 @default.
- W2914798412 cites W2340814775 @default.
- W2914798412 cites W2416447890 @default.
- W2914798412 cites W2484635499 @default.
- W2914798412 cites W2486731395 @default.
- W2914798412 cites W2551893829 @default.
- W2914798412 cites W2578469701 @default.