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• W2914798839 startingPage "211" @default.
• W2914798839 abstract "Abstract The immunomodulatory properties of exopolysaccharides (EPS), major components of bacterial biofilm, are not fully understood. Here, we examined the immunomodulatory potential of EPS derived from Bacillus licheniformis BioE-BL11 and Leuconostoc mesenteroides BioE-LMD18, isolated from Korean fermented kimchi. EPS from BioE-BL11 was composed of mannose (12.4%), galactose (1.82%), glucose (48.5%), fucose (37.1%), and arabinose (0.17%), and that from BioE-LMD18 was composed of mannose (8.71%), arabinose (0.07%), galactose (1.22%), glucose (79.8%), and fucose (10.21%). The highest EPS yield were obtained by incubation at 37 °C for 3 days with an initial pH of 7.0, without optimizing other conditions. The EPS from BioE-BL11 and BioE-LMD18 significantly inhibited secretion of the pro-inflammatory cytokine IL-6 in lipopolysaccharide-stimulated RAW264.7 mouse macrophage by 40.7% and 32.1%, respectively, enhanced secretion of the anti-inflammatory cytokine IL-10 in a dose-dependent manner, suggesting that EPS produced by these strains may be useful functional ingredients for the cosmetics, food, and pharmaceuticals industries." @default.
• W2914798839 created "2019-02-21" @default.
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• W2914798839 date "2019-03-01" @default.
• W2914798839 modified "2023-10-03" @default.
• W2914798839 title "Immunomodulatory effects of exopolysaccharides produced by Bacillus licheniformis and Leuconostoc mesenteroides isolated from Korean kimchi" @default.
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• W2914798839 doi "https://doi.org/10.1016/j.jff.2019.01.003" @default.
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