Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914856177> ?p ?o ?g. }
- W2914856177 endingPage "151" @default.
- W2914856177 startingPage "139" @default.
- W2914856177 abstract "The role of hyaluronan (HA) in periodontal healing has been speculated via its interaction with the CD44 receptor. While HA-CD44 interactions have previously been implicated in numerous cell types; effect and mechanism of exogenous HA on periodontal ligament (PDL) cells is less clear. Herein, we examine the effect of exogenous HA on contractility and migration in human and murine PDL cells using arrays of microposts and time-lapse microscopy. Our findings observed HA-treated human PDL cells as more contractile and less migratory than untreated cells. Moreover, the effect of HA on contractility and focal adhesion area was abrogated when PDL cells were treated with Y27632, an inhibitor of rho-dependent kinase, but not when these cells were treated with ML-7, an inhibitor of myosin light chain kinase. Our results provide insight into the mechanobiology of PDL cells, which may contribute towards the development of therapeutic strategies for periodontal healing and tissue regeneration." @default.
- W2914856177 created "2019-02-21" @default.
- W2914856177 creator A5033501255 @default.
- W2914856177 creator A5039825428 @default.
- W2914856177 creator A5064896875 @default.
- W2914856177 creator A5067125661 @default.
- W2914856177 creator A5072257672 @default.
- W2914856177 creator A5073085334 @default.
- W2914856177 date "2019-01-01" @default.
- W2914856177 modified "2023-09-25" @default.
- W2914856177 title "Hyaluronan-CD44 interactions mediate contractility and migration in periodontal ligament cells" @default.
- W2914856177 cites W126482535 @default.
- W2914856177 cites W1568020570 @default.
- W2914856177 cites W1598962581 @default.
- W2914856177 cites W1641373239 @default.
- W2914856177 cites W1794039655 @default.
- W2914856177 cites W1801147305 @default.
- W2914856177 cites W1964611109 @default.
- W2914856177 cites W1967265143 @default.
- W2914856177 cites W1967548677 @default.
- W2914856177 cites W1971512873 @default.
- W2914856177 cites W1974372984 @default.
- W2914856177 cites W1975091217 @default.
- W2914856177 cites W1979651146 @default.
- W2914856177 cites W1989197126 @default.
- W2914856177 cites W1989439022 @default.
- W2914856177 cites W1992856522 @default.
- W2914856177 cites W1993264286 @default.
- W2914856177 cites W1997777663 @default.
- W2914856177 cites W2002367182 @default.
- W2914856177 cites W2015472266 @default.
- W2914856177 cites W2015589988 @default.
- W2914856177 cites W2017181707 @default.
- W2914856177 cites W2018699957 @default.
- W2914856177 cites W2019125384 @default.
- W2914856177 cites W2021564917 @default.
- W2914856177 cites W2023675877 @default.
- W2914856177 cites W2024244222 @default.
- W2914856177 cites W2024372804 @default.
- W2914856177 cites W2024974747 @default.
- W2914856177 cites W2025037730 @default.
- W2914856177 cites W2027055494 @default.
- W2914856177 cites W2032476570 @default.
- W2914856177 cites W2037632318 @default.
- W2914856177 cites W2041033836 @default.
- W2914856177 cites W2043709380 @default.
- W2914856177 cites W2047533360 @default.
- W2914856177 cites W2051078628 @default.
- W2914856177 cites W2056563854 @default.
- W2914856177 cites W2062539033 @default.
- W2914856177 cites W2069207562 @default.
- W2914856177 cites W2077080652 @default.
- W2914856177 cites W2087490237 @default.
- W2914856177 cites W2098992617 @default.
- W2914856177 cites W2099285233 @default.
- W2914856177 cites W2101602694 @default.
- W2914856177 cites W2101837915 @default.
- W2914856177 cites W2106618287 @default.
- W2914856177 cites W2111585553 @default.
- W2914856177 cites W2112320300 @default.
- W2914856177 cites W2112924183 @default.
- W2914856177 cites W2114790022 @default.
- W2914856177 cites W2118544280 @default.
- W2914856177 cites W2119545055 @default.
- W2914856177 cites W2125527918 @default.
- W2914856177 cites W2125540465 @default.
- W2914856177 cites W2129148348 @default.
- W2914856177 cites W2134263002 @default.
- W2914856177 cites W2137231634 @default.
- W2914856177 cites W2140481166 @default.
- W2914856177 cites W2141416258 @default.
- W2914856177 cites W2141444608 @default.
- W2914856177 cites W2143623375 @default.
- W2914856177 cites W2145261791 @default.
- W2914856177 cites W2150050414 @default.
- W2914856177 cites W2150102283 @default.
- W2914856177 cites W2153352377 @default.
- W2914856177 cites W2154156610 @default.
- W2914856177 cites W2155879793 @default.
- W2914856177 cites W2156193902 @default.
- W2914856177 cites W2164082220 @default.
- W2914856177 cites W2261162807 @default.
- W2914856177 cites W8794497 @default.
- W2914856177 doi "https://doi.org/10.1080/19336918.2019.1568140" @default.
- W2914856177 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6527381" @default.
- W2914856177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30676222" @default.
- W2914856177 hasPublicationYear "2019" @default.
- W2914856177 type Work @default.
- W2914856177 sameAs 2914856177 @default.
- W2914856177 citedByCount "15" @default.
- W2914856177 countsByYear W29148561772020 @default.
- W2914856177 countsByYear W29148561772021 @default.
- W2914856177 countsByYear W29148561772022 @default.
- W2914856177 countsByYear W29148561772023 @default.
- W2914856177 crossrefType "journal-article" @default.
- W2914856177 hasAuthorship W2914856177A5033501255 @default.
- W2914856177 hasAuthorship W2914856177A5039825428 @default.
- W2914856177 hasAuthorship W2914856177A5064896875 @default.