FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914871041> ?p ?o ?g. }

• W2914871041 abstract "An isolated uncharged hydrogen bond acceptor such as the carbonyl functionality of an aldehyde or a keto group is absent in natural amino acids. Although glutamine and asparagine are known to hydrogen bond through the amide carbonyl group in their side chains, they also possess the amide NH 2 group, which can act as a hydrogen bond donor. This makes the structural study of peptides containing an oxo residue, with an isolated carbonyl group in the side chain, interesting. Here, we report the synthesis of δ‐ and ε‐oxo amino acids and their incorporation into oligopeptides as the N‐terminal residue. The resultant oxo peptides were extensively studied using X‐ray crystallography to understand the interactions offered by the oxo group in peptide crystals. We find that the oxo groups are capable of providing additional hydrogen bonding opportunities to the peptides, resulting in increased intermolecular interactions in crystals. The study thus offers avenues for the utilization of oxo residues to introduce intermolecular interactions in synthetic peptides." @default.
• W2914871041 created "2019-02-21" @default.
• W2914871041 creator A5004312934 @default.
• W2914871041 creator A5061385593 @default.
• W2914871041 creator A5064535076 @default.
• W2914871041 creator A5081675427 @default.
• W2914871041 creator A5085662564 @default.
• W2914871041 date "2019-01-29" @default.
• W2914871041 modified "2023-09-27" @default.
• W2914871041 title "Synthesis of peptides containing oxo amino acids and their crystallographic analysis" @default.
• W2914871041 cites W1963673259 @default.
• W2914871041 cites W1983732912 @default.
• W2914871041 cites W1991673513 @default.
• W2914871041 cites W1992094448 @default.
• W2914871041 cites W1992453786 @default.
• W2914871041 cites W1995996704 @default.
• W2914871041 cites W2001599007 @default.
• W2914871041 cites W2006225923 @default.
• W2914871041 cites W2018326618 @default.
• W2914871041 cites W2022422018 @default.
• W2914871041 cites W2026591577 @default.
• W2914871041 cites W2048221161 @default.
• W2914871041 cites W2056894945 @default.
• W2914871041 cites W2081359387 @default.
• W2914871041 cites W2127960367 @default.
• W2914871041 cites W2132454074 @default.
• W2914871041 cites W2155921797 @default.
• W2914871041 cites W2172280914 @default.
• W2914871041 cites W2197964340 @default.
• W2914871041 cites W2322000951 @default.
• W2914871041 cites W2322972210 @default.
• W2914871041 cites W2949182636 @default.
• W2914871041 cites W2952109782 @default.
• W2914871041 cites W2952951500 @default.
• W2914871041 cites W4210961063 @default.
• W2914871041 doi "https://doi.org/10.1002/psc.3148" @default.
• W2914871041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30697868" @default.
• W2914871041 hasPublicationYear "2019" @default.
• W2914871041 type Work @default.
• W2914871041 sameAs 2914871041 @default.
• W2914871041 citedByCount "2" @default.
• W2914871041 countsByYear W29148710412019 @default.
• W2914871041 countsByYear W29148710412023 @default.
• W2914871041 crossrefType "journal-article" @default.
• W2914871041 hasAuthorship W2914871041A5004312934 @default.
• W2914871041 hasAuthorship W2914871041A5061385593 @default.
• W2914871041 hasAuthorship W2914871041A5064535076 @default.
• W2914871041 hasAuthorship W2914871041A5081675427 @default.
• W2914871041 hasAuthorship W2914871041A5085662564 @default.
• W2914871041 hasConcept C112887158 @default.
• W2914871041 hasConcept C121332964 @default.
• W2914871041 hasConcept C13935069 @default.
• W2914871041 hasConcept C161790260 @default.
• W2914871041 hasConcept C166950319 @default.
• W2914871041 hasConcept C178790620 @default.
• W2914871041 hasConcept C185592680 @default.
• W2914871041 hasConcept C204921945 @default.
• W2914871041 hasConcept C26873012 @default.
• W2914871041 hasConcept C2775895851 @default.
• W2914871041 hasConcept C2778439535 @default.
• W2914871041 hasConcept C2779281246 @default.
• W2914871041 hasConcept C2779349466 @default.
• W2914871041 hasConcept C2779825165 @default.
• W2914871041 hasConcept C2779892579 @default.
• W2914871041 hasConcept C2781338088 @default.
• W2914871041 hasConcept C31684184 @default.
• W2914871041 hasConcept C32909587 @default.
• W2914871041 hasConcept C515207424 @default.
• W2914871041 hasConcept C521977710 @default.
• W2914871041 hasConcept C55493867 @default.
• W2914871041 hasConcept C71240020 @default.
• W2914871041 hasConceptScore W2914871041C112887158 @default.
• W2914871041 hasConceptScore W2914871041C121332964 @default.
• W2914871041 hasConceptScore W2914871041C13935069 @default.
• W2914871041 hasConceptScore W2914871041C161790260 @default.
• W2914871041 hasConceptScore W2914871041C166950319 @default.
• W2914871041 hasConceptScore W2914871041C178790620 @default.
• W2914871041 hasConceptScore W2914871041C185592680 @default.
• W2914871041 hasConceptScore W2914871041C204921945 @default.
• W2914871041 hasConceptScore W2914871041C26873012 @default.
• W2914871041 hasConceptScore W2914871041C2775895851 @default.
• W2914871041 hasConceptScore W2914871041C2778439535 @default.
• W2914871041 hasConceptScore W2914871041C2779281246 @default.
• W2914871041 hasConceptScore W2914871041C2779349466 @default.
• W2914871041 hasConceptScore W2914871041C2779825165 @default.
• W2914871041 hasConceptScore W2914871041C2779892579 @default.
• W2914871041 hasConceptScore W2914871041C2781338088 @default.
• W2914871041 hasConceptScore W2914871041C31684184 @default.
• W2914871041 hasConceptScore W2914871041C32909587 @default.
• W2914871041 hasConceptScore W2914871041C515207424 @default.
• W2914871041 hasConceptScore W2914871041C521977710 @default.
• W2914871041 hasConceptScore W2914871041C55493867 @default.
• W2914871041 hasConceptScore W2914871041C71240020 @default.
• W2914871041 hasFunder F4320334771 @default.
• W2914871041 hasIssue "3" @default.
• W2914871041 hasLocation W29148710411 @default.
• W2914871041 hasLocation W29148710412 @default.
• W2914871041 hasOpenAccess W2914871041 @default.
• W2914871041 hasPrimaryLocation W29148710411 @default.
• W2914871041 hasRelatedWork W1965659262 @default.

• next