Matches in SemOpenAlex for { <https://semopenalex.org/work/W2914885029> ?p ?o ?g. }
- W2914885029 endingPage "175" @default.
- W2914885029 startingPage "168" @default.
- W2914885029 abstract "Low concentration of LPS can be detected in healthy mammals without triggering systemic inflammation. Here we analysed the influence of the mycotoxin deoxynivalenol (DON) on very low LPS concentrations and the role of DON in the physiology of pigs challenged with high artificial LPS dosage mimicking septic shock. Pigs were fed for 29 d with DON-contaminated (4.59 mg/kg feed) or control feed. Samples of control animals showed 6.6 ± 13.5 pg/ml LPS in portal and 3.1 ± 7.6 pg/ml LPS in jugular serum samples. In the DON fed group, 3.4 ± 7.2 pg/ml and 0.6 ± 0.8 pg/ml were detected. The differences were statistically not significant, indicating that DON is not a trigger for enhanced LPS transfer into the blood circulation. Next, pigs were challenged with 7.5 µg LPS/kg body mass via portal or jugular route. The application route did not significantly influence the LPS concentration. We expected higher circulating LPS concentrations in the presence of DON due to the additional stress of liver metabolism and reduced liver capacity to remove LPS from circulation. This scenario is supported by tendency. In summary, we found that DON is unlikely to influence LPS transfer in the gut; DON likely reduces the capacity for LPS removal in septic shock conditions." @default.
- W2914885029 created "2019-02-21" @default.
- W2914885029 creator A5005558184 @default.
- W2914885029 creator A5016325133 @default.
- W2914885029 creator A5026470015 @default.
- W2914885029 creator A5052687526 @default.
- W2914885029 creator A5064876086 @default.
- W2914885029 creator A5068271729 @default.
- W2914885029 creator A5073664283 @default.
- W2914885029 creator A5075037428 @default.
- W2914885029 creator A5082706506 @default.
- W2914885029 date "2019-02-13" @default.
- W2914885029 modified "2023-10-12" @default.
- W2914885029 title "Effects of deoxynivalenol-feed contamination on circulating LPS in pigs" @default.
- W2914885029 cites W169399554 @default.
- W2914885029 cites W1964954110 @default.
- W2914885029 cites W1974546936 @default.
- W2914885029 cites W1988279036 @default.
- W2914885029 cites W2018815492 @default.
- W2914885029 cites W2022387897 @default.
- W2914885029 cites W2023007981 @default.
- W2914885029 cites W2028729075 @default.
- W2914885029 cites W2029685880 @default.
- W2914885029 cites W2030458379 @default.
- W2914885029 cites W2044948009 @default.
- W2914885029 cites W2047580124 @default.
- W2914885029 cites W2053977755 @default.
- W2914885029 cites W2073578515 @default.
- W2914885029 cites W2083260532 @default.
- W2914885029 cites W2086482784 @default.
- W2914885029 cites W2089679298 @default.
- W2914885029 cites W2095895883 @default.
- W2914885029 cites W2110791654 @default.
- W2914885029 cites W2117307634 @default.
- W2914885029 cites W2120932839 @default.
- W2914885029 cites W2131536322 @default.
- W2914885029 cites W2143903606 @default.
- W2914885029 cites W2159745814 @default.
- W2914885029 cites W2168118833 @default.
- W2914885029 cites W2174491121 @default.
- W2914885029 cites W2178116278 @default.
- W2914885029 cites W2191865519 @default.
- W2914885029 cites W2218863722 @default.
- W2914885029 cites W2227319970 @default.
- W2914885029 cites W2241474374 @default.
- W2914885029 cites W2276780135 @default.
- W2914885029 cites W2328023807 @default.
- W2914885029 cites W2345801223 @default.
- W2914885029 cites W2594535820 @default.
- W2914885029 cites W2611136196 @default.
- W2914885029 cites W2611659474 @default.
- W2914885029 cites W4312183866 @default.
- W2914885029 doi "https://doi.org/10.1177/1753425919829552" @default.
- W2914885029 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6830939" @default.
- W2914885029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30760085" @default.
- W2914885029 hasPublicationYear "2019" @default.
- W2914885029 type Work @default.
- W2914885029 sameAs 2914885029 @default.
- W2914885029 citedByCount "6" @default.
- W2914885029 countsByYear W29148850292020 @default.
- W2914885029 countsByYear W29148850292021 @default.
- W2914885029 countsByYear W29148850292022 @default.
- W2914885029 countsByYear W29148850292023 @default.
- W2914885029 crossrefType "journal-article" @default.
- W2914885029 hasAuthorship W2914885029A5005558184 @default.
- W2914885029 hasAuthorship W2914885029A5016325133 @default.
- W2914885029 hasAuthorship W2914885029A5026470015 @default.
- W2914885029 hasAuthorship W2914885029A5052687526 @default.
- W2914885029 hasAuthorship W2914885029A5064876086 @default.
- W2914885029 hasAuthorship W2914885029A5068271729 @default.
- W2914885029 hasAuthorship W2914885029A5073664283 @default.
- W2914885029 hasAuthorship W2914885029A5075037428 @default.
- W2914885029 hasAuthorship W2914885029A5082706506 @default.
- W2914885029 hasBestOaLocation W29148850291 @default.
- W2914885029 hasConcept C126322002 @default.
- W2914885029 hasConcept C134018914 @default.
- W2914885029 hasConcept C140793950 @default.
- W2914885029 hasConcept C185592680 @default.
- W2914885029 hasConcept C203014093 @default.
- W2914885029 hasConcept C2776165368 @default.
- W2914885029 hasConcept C2776914184 @default.
- W2914885029 hasConcept C2777628635 @default.
- W2914885029 hasConcept C2778384902 @default.
- W2914885029 hasConcept C2778754761 @default.
- W2914885029 hasConcept C31903555 @default.
- W2914885029 hasConcept C42407357 @default.
- W2914885029 hasConcept C57194454 @default.
- W2914885029 hasConcept C71924100 @default.
- W2914885029 hasConcept C84699730 @default.
- W2914885029 hasConcept C86803240 @default.
- W2914885029 hasConceptScore W2914885029C126322002 @default.
- W2914885029 hasConceptScore W2914885029C134018914 @default.
- W2914885029 hasConceptScore W2914885029C140793950 @default.
- W2914885029 hasConceptScore W2914885029C185592680 @default.
- W2914885029 hasConceptScore W2914885029C203014093 @default.
- W2914885029 hasConceptScore W2914885029C2776165368 @default.
- W2914885029 hasConceptScore W2914885029C2776914184 @default.
- W2914885029 hasConceptScore W2914885029C2777628635 @default.