FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915192914> ?p ?o ?g. }

• W2915192914 endingPage "8" @default.
• W2915192914 startingPage "1" @default.
• W2915192914 abstract "Background . Antiretroviral treatment may lead to the emergence of HIV drug resistance, which can be transmitted. HIV primary drug resistance (PDR) is of great public health concern because it has the potential to compromise the efficacy of antiretroviral therapy (ART) at the population level. Objective . To estimate the level of primary drug resistance among recently infected cases of HIV in 6 ART centres of North-Western India from September 2014 to June 2016. Methods . The level of primary drug resistance was studied among 37 recently infected HIV cases identified by Limiting antigen (Lag) avidity assay based on modified Recent Infection Testing Algorithm (RITA). The reverse transcriptase region of HIV-1 pol gene (1-268 codons) was genotyped. The sequences were analyzed using the Calibrated Population Resistance (CPR) tool of Stanford University HIV drug resistance (DR) database to identify drug resistance. Results . Among 37 isolates studied, 6 (16.2%) samples showed primary drug resistance (PDR) against reverse transcriptase (RT) inhibitor. The proportion of primary drug resistance was 22.2% (2/9) among female sex workers, 14.3% (1/7) among men having sex with men, and 14.3% (3/21) among injecting drug users. Observed mutations were K219R, L74V, K219N, and Y181C. Injecting drug user (IDU) has showed resistance to either nucleoside/nucleotide reverse transcriptase inhibitors (NRTI) or nonnucleotide reverse transcriptase inhibitors (NNRTI). Conclusion . Resistance to either NRTI or NNRTI among the recently is a new challenge that needs to be addressed. The fact that both Y181C isolates are IDUs is important and represents 2/21 (~10%) NNRTI drug resistance. Surveillance for primary drug resistance (PDR) needs to be integrated into next generation of HIV surveillance as access to ART is increasing due to introduction of test and treat policy." @default.
• W2915192914 created "2019-03-02" @default.
• W2915192914 creator A5016810539 @default.
• W2915192914 creator A5021876378 @default.
• W2915192914 creator A5052802492 @default.
• W2915192914 creator A5067168625 @default.
• W2915192914 creator A5074832178 @default.
• W2915192914 creator A5076066988 @default.
• W2915192914 date "2019-02-27" @default.
• W2915192914 modified "2023-09-24" @default.
• W2915192914 title "Primary HIV Drug Resistance among Recently Infected Cases of HIV in North-West India" @default.
• W2915192914 cites W1546124393 @default.
• W2915192914 cites W1867188112 @default.
• W2915192914 cites W1984502945 @default.
• W2915192914 cites W1992621922 @default.
• W2915192914 cites W2018112385 @default.
• W2915192914 cites W2021809965 @default.
• W2915192914 cites W2023970514 @default.
• W2915192914 cites W2026787430 @default.
• W2915192914 cites W2027095254 @default.
• W2915192914 cites W2033353520 @default.
• W2915192914 cites W2036549899 @default.
• W2915192914 cites W2036883885 @default.
• W2915192914 cites W2068751404 @default.
• W2915192914 cites W2074585333 @default.
• W2915192914 cites W2082116548 @default.
• W2915192914 cites W2086448238 @default.
• W2915192914 cites W2088290139 @default.
• W2915192914 cites W2093550389 @default.
• W2915192914 cites W2104162334 @default.
• W2915192914 cites W2109483059 @default.
• W2915192914 cites W2119358638 @default.
• W2915192914 cites W2123613937 @default.
• W2915192914 cites W2124809542 @default.
• W2915192914 cites W2141149454 @default.
• W2915192914 cites W2152896082 @default.
• W2915192914 cites W2153907871 @default.
• W2915192914 cites W2288991225 @default.
• W2915192914 cites W2320809081 @default.
• W2915192914 cites W65942279 @default.
• W2915192914 doi "https://doi.org/10.1155/2019/1525646" @default.
• W2915192914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6415312" @default.
• W2915192914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30937190" @default.
• W2915192914 hasPublicationYear "2019" @default.
• W2915192914 type Work @default.
• W2915192914 sameAs 2915192914 @default.
• W2915192914 citedByCount "5" @default.
• W2915192914 countsByYear W29151929142020 @default.
• W2915192914 countsByYear W29151929142021 @default.
• W2915192914 countsByYear W29151929142022 @default.
• W2915192914 crossrefType "journal-article" @default.
• W2915192914 hasAuthorship W2915192914A5016810539 @default.
• W2915192914 hasAuthorship W2915192914A5021876378 @default.
• W2915192914 hasAuthorship W2915192914A5052802492 @default.
• W2915192914 hasAuthorship W2915192914A5067168625 @default.
• W2915192914 hasAuthorship W2915192914A5074832178 @default.
• W2915192914 hasAuthorship W2915192914A5076066988 @default.
• W2915192914 hasBestOaLocation W29151929141 @default.
• W2915192914 hasConcept C104317684 @default.
• W2915192914 hasConcept C114851261 @default.
• W2915192914 hasConcept C142462285 @default.
• W2915192914 hasConcept C156719811 @default.
• W2915192914 hasConcept C159047783 @default.
• W2915192914 hasConcept C2777351918 @default.
• W2915192914 hasConcept C2778451633 @default.
• W2915192914 hasConcept C2780035454 @default.
• W2915192914 hasConcept C2908647359 @default.
• W2915192914 hasConcept C2909970146 @default.
• W2915192914 hasConcept C2993143319 @default.
• W2915192914 hasConcept C3013748606 @default.
• W2915192914 hasConcept C49105822 @default.
• W2915192914 hasConcept C54355233 @default.
• W2915192914 hasConcept C71924100 @default.
• W2915192914 hasConcept C86803240 @default.
• W2915192914 hasConcept C89423630 @default.
• W2915192914 hasConcept C98274493 @default.
• W2915192914 hasConcept C99454951 @default.
• W2915192914 hasConceptScore W2915192914C104317684 @default.
• W2915192914 hasConceptScore W2915192914C114851261 @default.
• W2915192914 hasConceptScore W2915192914C142462285 @default.
• W2915192914 hasConceptScore W2915192914C156719811 @default.
• W2915192914 hasConceptScore W2915192914C159047783 @default.
• W2915192914 hasConceptScore W2915192914C2777351918 @default.
• W2915192914 hasConceptScore W2915192914C2778451633 @default.
• W2915192914 hasConceptScore W2915192914C2780035454 @default.
• W2915192914 hasConceptScore W2915192914C2908647359 @default.
• W2915192914 hasConceptScore W2915192914C2909970146 @default.
• W2915192914 hasConceptScore W2915192914C2993143319 @default.
• W2915192914 hasConceptScore W2915192914C3013748606 @default.
• W2915192914 hasConceptScore W2915192914C49105822 @default.
• W2915192914 hasConceptScore W2915192914C54355233 @default.
• W2915192914 hasConceptScore W2915192914C71924100 @default.
• W2915192914 hasConceptScore W2915192914C86803240 @default.
• W2915192914 hasConceptScore W2915192914C89423630 @default.
• W2915192914 hasConceptScore W2915192914C98274493 @default.
• W2915192914 hasConceptScore W2915192914C99454951 @default.
• W2915192914 hasLocation W29151929141 @default.
• W2915192914 hasLocation W29151929142 @default.

• next